ID   VPB_HAEIN               Reviewed;         287 AA.
AC   P96343;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Mu-like prophage FluMu DNA transposition protein B;
GN   OrderedLocusNames=HI_1481;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: This protein is a non-specific DNA-binding and ATP-
CC       hydrolyzing protein essential for bacteriophage integration and
CC       replication. {ECO:0000250}.
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DR   EMBL; L42023; AAC23126.1; -; Genomic_DNA.
DR   PIR; C64126; C64126.
DR   RefSeq; NP_439632.1; NC_000907.1.
DR   RefSeq; WP_010869222.1; NC_000907.1.
DR   AlphaFoldDB; P96343; -.
DR   SMR; P96343; -.
DR   STRING; 71421.HI_1481; -.
DR   EnsemblBacteria; AAC23126; AAC23126; HI_1481.
DR   KEGG; hin:HI_1481; -.
DR   PATRIC; fig|71421.8.peg.1548; -.
DR   eggNOG; COG2842; Bacteria.
DR   HOGENOM; CLU_056183_1_0_6; -.
DR   OMA; HEYARLW; -.
DR   PhylomeDB; P96343; -.
DR   BioCyc; HINF71421:G1GJ1-1506-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.1180.10; -; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR036733; B_transposit_C_sf.
DR   InterPro; IPR009084; B_transpositn_C.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF13401; AAA_22; 1.
DR   Pfam; PF09077; Phage-MuB_C; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF47681; SSF47681; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA integration; DNA replication; DNA-binding;
KW   Nucleotide-binding; Reference proteome; Transposition.
FT   CHAIN           1..287
FT                   /note="Mu-like prophage FluMu DNA transposition protein B"
FT                   /id="PRO_0000149719"
FT   DOMAIN          7..62
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        18..37
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   BINDING         98..105
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   287 AA;  31488 MW;  5BAA47FE2BD03DC3 CRC64;
     MTLINKLKQH LSDSQITQAQ LAREAGVNAG ALSAYLNDNY KGNIADVEAK LAAYLEKKAV
     QAREFVEAPA FIETATSRQI FKTLEFAQIA NCLATVYGMS GVGKTKAIQE FAKSHANVWL
     VTASPSRSSL SEILYEIALE LGISDAPRRK GTLSRLIARK IKGTEGLLIV DEADHLPYEA
     LEELRIMQEE AGIGLVLVGN DKVYTRMKGG ISPSHEYARL WSRVAKNTSI QKTKKADTQA
     VAQAWGLETD EEALKVMQSI TETGGGLRIL TQTYACRNGS KRIWQVD