ID   VPIP_BPT4               Reviewed;          80 AA.
AC   P03720;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   23-FEB-2022, entry version 79.
DE   RecName: Full=Prehead core component PIP;
DE   AltName: Full=Protein Gp67;
DE   Contains:
DE     RecName: Full=Internal peptide II;
GN   Name=67;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7154087; DOI=10.1016/0022-2836(82)90402-8;
RA   Voelker T.A., Gafner J., Bickle T.A., Showe M.K.;
RT   "Gene 67, a new, essential bacteriophage T4 head gene codes for a prehead
RT   core component, PIP. I. Genetic mapping and DNA sequence.";
RL   J. Mol. Biol. 161:479-489(1982).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-3.
RC   STRAIN=D;
RX   PubMed=2798102; DOI=10.1093/nar/17.18.7514;
RA   Marusich E.I., Mesyanzhinov V.V.;
RT   "Nucleotide and deduced amino acid sequences of bacteriophage T4 gene 20.";
RL   Nucleic Acids Res. 17:7514-7514(1989).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 53-80.
RX   PubMed=6512858; DOI=10.1016/0022-2836(84)90073-1;
RA   Keller B., Sengstag C., Kellenberger E., Bickle T.A.;
RT   "Gene 68, a new bacteriophage T4 gene which codes for the 17K prohead core
RT   protein is involved in head size determination.";
RL   J. Mol. Biol. 179:415-430(1984).
CC   -!- FUNCTION: The production of one phage particle requires 250 copies of
CC       PIP. During head maturation, PIP is cleaved to form the stable head
CC       constituent, internal peptide II.
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DR   EMBL; X16055; CAA34191.1; -; Genomic_DNA.
DR   EMBL; AF158101; AAD42515.1; -; Genomic_DNA.
DR   EMBL; J02512; AAA32520.1; -; Genomic_DNA.
DR   EMBL; X01414; CAA25655.1; -; Genomic_DNA.
DR   PIR; A04347; HIBPT4.
DR   RefSeq; NP_049783.1; NC_000866.4.
DR   SMR; P03720; -.
DR   PRIDE; P03720; -.
DR   GeneID; 1258665; -.
DR   KEGG; vg:1258665; -.
DR   Proteomes; UP000009087; Genome.
DR   InterPro; IPR035114; GP67.
DR   Pfam; PF17634; GP67; 1.
PE   4: Predicted;
KW   Reference proteome; Viral release from host cell.
FT   CHAIN           1..80
FT                   /note="Prehead core component PIP"
FT                   /id="PRO_0000003344"
FT   CHAIN           47..80
FT                   /note="Internal peptide II"
FT                   /id="PRO_0000003345"
FT   REGION          43..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        47..80
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            46..47
FT                   /note="Cleavage; by prohead core protease GP21"
SQ   SEQUENCE   80 AA;  9106 MW;  BEFA87A10D9AA47A CRC64;
     MEGLIEAIKS NDLVAARKLF AEAMAARTID LIKEEKIAIA RNFLIEGEEP EDEDEDEDDE
     DSDDKDDKKD EDSDEDEDDE