ID   VPRL_OMVVS              Reviewed;          94 AA.
AC   P16904;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   29-SEP-2021, entry version 64.
DE   RecName: Full=Probable Vpr-like protein;
DE   AltName: Full=Protein S;
DE   AltName: Full=Protein Tat;
GN   Name=tat;
OS   Ovine maedi visna related virus (strain South Africa) (SA-OMVV) (Ovine
OS   lentivirus).
OC   Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC   Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX   NCBI_TaxID=11664;
OH   NCBI_TaxID=9940; Ovis aries (Sheep).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2158181; DOI=10.1016/0042-6822(90)90428-t;
RA   Querat G., Audoly G., Sonigo P., Vigne R.;
RT   "Nucleotide sequence analysis of SA-OMVV, a visna-related ovine lentivirus:
RT   phylogenetic history of lentiviruses.";
RL   Virology 175:434-447(1990).
CC   -!- FUNCTION: Seems to function as a Vpr-like protein, since it mediates
CC       host cell cycle arrest in G2 phase. Cell cycle arrest creates a
CC       favorable environment for maximizing viral expression and production
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Host nucleus.
CC   -!- CAUTION: Was first thought to be the equivalent of lentiviral Tat
CC       protein, but it does not induce any transactivation of viral LTR
CC       promoter, or if any, at very low rate. The LTR promoter of this virus
CC       has a high basal activity and does apparently not need transactivation
CC       by a Tat-like protein. {ECO:0000305}.
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DR   EMBL; M34193; AAA46782.1; -; Genomic_DNA.
DR   EMBL; M31646; AAA66815.1; -; Genomic_RNA.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   InterPro; IPR004247; Lentiviral_Vpr-like.
DR   Pfam; PF02998; Lentiviral_Tat; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Host nucleus; Virion.
FT   CHAIN           1..94
FT                   /note="Probable Vpr-like protein"
FT                   /id="PRO_0000085489"
SQ   SEQUENCE   94 AA;  11285 MW;  7C9B26AB3D780149 CRC64;
     MEEAPRRRPG GSREAEGIFR YYEDWECWDH VSQRVPNEVL QRWLAMLTNN QLRRKVIREA
     QIWMWKNANA PIRRNCGCRL CNPGWGSQVR DVEL