VPS92_SCHPO
ID VPS92_SCHPO Reviewed; 402 AA.
AC O94388; D2CFN7;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=Vacuolar protein sorting-associated protein 9b;
DE AltName: Full=Vacuolar protein-targeting protein 9b;
GN Name=vps902; Synonyms=vps9b; ORFNames=SPBC29A10.11c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Miyamoto M., Saito N., Matsuda T.;
RT "Schizosaccharomyces pombe Vps9 protein mRNA, complete cds.";
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-355, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
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DR EMBL; DQ665300; ABG66957.1; -; mRNA.
DR EMBL; CU329671; CAA22439.1; -; Genomic_DNA.
DR PIR; T40066; T40066.
DR RefSeq; NP_596056.1; NM_001021967.2.
DR AlphaFoldDB; O94388; -.
DR SMR; O94388; -.
DR BioGRID; 276913; 7.
DR STRING; 4896.SPBC29A10.11c.1; -.
DR iPTMnet; O94388; -.
DR MaxQB; O94388; -.
DR PaxDb; O94388; -.
DR PRIDE; O94388; -.
DR EnsemblFungi; SPBC29A10.11c.1; SPBC29A10.11c.1:pep; SPBC29A10.11c.
DR PomBase; SPBC29A10.11c; vps902.
DR VEuPathDB; FungiDB:SPBC29A10.11c; -.
DR eggNOG; KOG2319; Eukaryota.
DR HOGENOM; CLU_689192_0_0_1; -.
DR InParanoid; O94388; -.
DR OMA; MFHTPPI; -.
DR PhylomeDB; O94388; -.
DR PRO; PR:O94388; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0030139; C:endocytic vesicle; IBA:GO_Central.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISM:PomBase.
DR GO; GO:0031267; F:small GTPase binding; IBA:GO_Central.
DR GO; GO:0016192; P:vesicle-mediated transport; ISO:PomBase.
DR Gene3D; 1.20.1050.80; -; 1.
DR InterPro; IPR003123; VPS9.
DR InterPro; IPR045046; Vps9-like.
DR InterPro; IPR037191; VPS9_dom_sf.
DR PANTHER; PTHR23101; PTHR23101; 1.
DR Pfam; PF02204; VPS9; 1.
DR SMART; SM00167; VPS9; 1.
DR SUPFAM; SSF109993; SSF109993; 1.
DR PROSITE; PS51205; VPS9; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; GTPase activation; Phosphoprotein; Reference proteome.
FT CHAIN 1..402
FT /note="Vacuolar protein sorting-associated protein 9b"
FT /id="PRO_0000316572"
FT DOMAIN 139..278
FT /note="VPS9"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00550"
FT MOD_RES 355
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 402 AA; 45297 MW; 7752E431981579D6 CRC64;
MSFLNSWRAV KYTNKPKEED IKLPNSASNL PTTVQACVIQ FISSLVSPVH PQLLSPEELA
KAFQNFYKHT DEFIASTLIP QPSSKDQNVP LLFPEEIDAQ KKARQHLLNQ KDEWMDQIED
IVCEYLYDRI FCLSTSTDAA KDDLLKKFIA SEEKKELINC IPIPDDEKLT NRLHEVSEAF
FALDEQHTPR SKINTFMTVN SSILNASQLP QEELNADSLL NLTIYCILCY PGFHLISHLN
FVLRFRNADF LSGEQRYCLT TFEAALTFIL RACPNLLTQS SIQPSDDPLS LEVANSETVS
TSNSLHDPSA EPYPVNRSSL SNLRNLGLAL EKSYASLLSK VANHTAKSSE DSSNSVEFVG
DPPLERFLTV SDASDLKIGE IELLLSDYKR LARLLFEKNG NQ
