VQ11_ARATH
ID VQ11_ARATH Reviewed; 177 AA.
AC Q9M8L3;
DT 04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=VQ motif-containing protein 11 {ECO:0000303|PubMed:22535423};
DE Short=AtVQ11 {ECO:0000303|PubMed:22535423};
DE AltName: Full=MPK3/6-targeted VQ-motif-containing protein 5 {ECO:0000303|PubMed:24750137};
GN Name=VQ11 {ECO:0000303|PubMed:22535423};
GN Synonyms=MVQ5 {ECO:0000303|PubMed:24750137};
GN OrderedLocusNames=At1g80450 {ECO:0000312|Araport:AT1G80450,
GN ECO:0000312|EMBL:AEE36406.1};
GN ORFNames=T21F11.22 {ECO:0000312|EMBL:AAF27124.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=22535423; DOI=10.1104/pp.112.196816;
RA Cheng Y., Zhou Y., Yang Y., Chi Y.J., Zhou J., Chen J.Y., Wang F., Fan B.,
RA Shi K., Zhou Y.H., Yu J.Q., Chen Z.;
RT "Structural and functional analysis of VQ motif-containing proteins in
RT Arabidopsis as interacting proteins of WRKY transcription factors.";
RL Plant Physiol. 159:810-825(2012).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND PHOSPHORYLATION AT SER-115 AND
RP SER-142.
RX PubMed=24750137; DOI=10.1111/nph.12817;
RA Pecher P., Eschen-Lippold L., Herklotz S., Kuhle K., Naumann K., Bethke G.,
RA Uhrig J., Weyhe M., Scheel D., Lee J.;
RT "The Arabidopsis thaliana mitogen-activated protein kinases MPK3 and MPK6
RT target a subclass of 'VQ-motif'-containing proteins to regulate immune
RT responses.";
RL New Phytol. 203:592-606(2014).
CC -!- FUNCTION: May modulate WRKY transcription factor activities.
CC {ECO:0000250|UniProtKB:Q9M9F0}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9M9F0}.
CC -!- PTM: Phosphorylated on serine residues by MPK6.
CC {ECO:0000269|PubMed:24750137}.
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DR EMBL; AC018849; AAF27124.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36406.1; -; Genomic_DNA.
DR EMBL; BT010842; AAR24209.1; -; mRNA.
DR EMBL; BT012614; AAT06433.1; -; mRNA.
DR PIR; C96836; C96836.
DR RefSeq; NP_178160.1; NM_106693.4.
DR AlphaFoldDB; Q9M8L3; -.
DR STRING; 3702.AT1G80450.1; -.
DR iPTMnet; Q9M8L3; -.
DR PaxDb; Q9M8L3; -.
DR PRIDE; Q9M8L3; -.
DR EnsemblPlants; AT1G80450.1; AT1G80450.1; AT1G80450.
DR GeneID; 844384; -.
DR Gramene; AT1G80450.1; AT1G80450.1; AT1G80450.
DR KEGG; ath:AT1G80450; -.
DR Araport; AT1G80450; -.
DR TAIR; locus:2198943; AT1G80450.
DR eggNOG; ENOG502S350; Eukaryota.
DR HOGENOM; CLU_069496_1_0_1; -.
DR InParanoid; Q9M8L3; -.
DR OMA; PNTTYVQ; -.
DR OrthoDB; 1376281at2759; -.
DR PhylomeDB; Q9M8L3; -.
DR PRO; PR:Q9M8L3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9M8L3; baseline and differential.
DR Genevisible; Q9M8L3; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR008889; VQ.
DR InterPro; IPR039826; VQ11.
DR InterPro; IPR039611; VQ_4/11/13/19/31/33.
DR PANTHER; PTHR33402; PTHR33402; 1.
DR PANTHER; PTHR33402:SF27; PTHR33402:SF27; 1.
DR Pfam; PF05678; VQ; 1.
PE 1: Evidence at protein level;
KW Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..177
FT /note="VQ motif-containing protein 11"
FT /id="PRO_0000432312"
FT REGION 115..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 25..34
FT /note="VQ"
FT /evidence="ECO:0000305"
FT COMPBIAS 115..133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 43
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5M750"
FT MOD_RES 99
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9LDZ1"
FT MOD_RES 115
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 142
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 145
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9FHZ3"
FT MOD_RES 161
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9LDZ1"
SQ SEQUENCE 177 AA; 19925 MW; FA981F68E4F3700F CRC64;
MSHQQPPSYA TEPNTMFVQA DPSNFRNIVQ KLTGAPPDIS SSSFSAVSAA HQKLPLTPKK
PAFKLHERRQ SSKKMELKVN NITNPNDAFS HFHRGFLVSP VSHLDPFWAR VSPHSAREEH
HAQPDKEEQK AIAEKGFYFL PSPRSGSEPA PELLPLFPLR SPNGTNHRIH EDNHRDS
