VQ13_ARATH
ID VQ13_ARATH Reviewed; 204 AA.
AC O23660; Q8L8C3;
DT 04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=VQ motif-containing protein 13 {ECO:0000303|PubMed:22535423};
DE Short=AtVQ13 {ECO:0000303|PubMed:22535423};
DE AltName: Full=MPK3/6-targeted VQ-motif-containing protein 2 {ECO:0000303|PubMed:24750137};
GN Name=VQ13 {ECO:0000303|PubMed:22535423};
GN Synonyms=MVQ2 {ECO:0000303|PubMed:24750137}; OrderedLocusNames=At2g33780;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=12481096; DOI=10.1104/pp.010207;
RA Xiao Y.-L., Malik M., Whitelaw C.A., Town C.D.;
RT "Cloning and sequencing of cDNAs for hypothetical genes from chromosome 2
RT of Arabidopsis.";
RL Plant Physiol. 130:2118-2128(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=22535423; DOI=10.1104/pp.112.196816;
RA Cheng Y., Zhou Y., Yang Y., Chi Y.J., Zhou J., Chen J.Y., Wang F., Fan B.,
RA Shi K., Zhou Y.H., Yu J.Q., Chen Z.;
RT "Structural and functional analysis of VQ motif-containing proteins in
RT Arabidopsis as interacting proteins of WRKY transcription factors.";
RL Plant Physiol. 159:810-825(2012).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND PHOSPHORYLATION AT SER-17;
RP THR-177; THR-192; SER-196 AND SER-200.
RX PubMed=24750137; DOI=10.1111/nph.12817;
RA Pecher P., Eschen-Lippold L., Herklotz S., Kuhle K., Naumann K., Bethke G.,
RA Uhrig J., Weyhe M., Scheel D., Lee J.;
RT "The Arabidopsis thaliana mitogen-activated protein kinases MPK3 and MPK6
RT target a subclass of 'VQ-motif'-containing proteins to regulate immune
RT responses.";
RL New Phytol. 203:592-606(2014).
CC -!- FUNCTION: May modulate WRKY transcription factor activities.
CC {ECO:0000250|UniProtKB:Q9M9F0}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9M9F0}.
CC -!- PTM: Phosphorylated on serine and threonine residues by MPK6.
CC {ECO:0000269|PubMed:24750137}.
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DR EMBL; U78721; AAC69144.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08884.1; -; Genomic_DNA.
DR EMBL; AY102548; AAM76753.1; -; mRNA.
DR EMBL; AY649267; AAT69184.1; -; Genomic_DNA.
DR PIR; E84749; E84749.
DR RefSeq; NP_180934.1; NM_128937.3.
DR AlphaFoldDB; O23660; -.
DR STRING; 3702.AT2G33780.1; -.
DR iPTMnet; O23660; -.
DR PaxDb; O23660; -.
DR PRIDE; O23660; -.
DR EnsemblPlants; AT2G33780.1; AT2G33780.1; AT2G33780.
DR GeneID; 817945; -.
DR Gramene; AT2G33780.1; AT2G33780.1; AT2G33780.
DR KEGG; ath:AT2G33780; -.
DR Araport; AT2G33780; -.
DR TAIR; locus:2057676; AT2G33780.
DR eggNOG; ENOG502RIDK; Eukaryota.
DR HOGENOM; CLU_069496_0_0_1; -.
DR InParanoid; O23660; -.
DR OrthoDB; 1494333at2759; -.
DR PhylomeDB; O23660; -.
DR PRO; PR:O23660; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O23660; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR008889; VQ.
DR InterPro; IPR039827; VQ4/VQ13.
DR InterPro; IPR039611; VQ_4/11/13/19/31/33.
DR PANTHER; PTHR33402; PTHR33402; 1.
DR PANTHER; PTHR33402:SF16; PTHR33402:SF16; 1.
DR Pfam; PF05678; VQ; 1.
PE 1: Evidence at protein level;
KW Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..204
FT /note="VQ motif-containing protein 13"
FT /id="PRO_0000432313"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 56..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 133..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 46..55
FT /note="VQ"
FT /evidence="ECO:0000305"
FT COMPBIAS 153..167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 17
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 73
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5M750"
FT MOD_RES 128
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9LDZ1"
FT MOD_RES 131
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q9LDZ1"
FT MOD_RES 147
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5M750"
FT MOD_RES 173
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5M750"
FT MOD_RES 177
FT /note="Phosphothreonine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 192
FT /note="Phosphothreonine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 196
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 200
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:24750137"
SQ SEQUENCE 204 AA; 23115 MW; 39A50EE7E11867D7 CRC64;
MEKSPRYRDK AKNLLPSPSS CTTTPTRYVK DDMYETTFIR TDPSSFKQVV QLLTGIPKNP
THQPDPRFPP FHSIPPIKAV TNKKQSSSFR LSERRNSMKH YLNINPTHSG PPEILTPTIL
NFPALDLSPD TPLMSDPFYR PGSFSQSPSD SKPSFDDDQE RSIKEKGFYL RPSPSTTPRD
TEPRLLSLFP MTPIHSPAPS PHDH
