VQ19_ARATH
ID VQ19_ARATH Reviewed; 219 AA.
AC Q9LDZ1;
DT 04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=VQ motif-containing protein 19 {ECO:0000303|PubMed:22535423};
DE Short=AtVQ19 {ECO:0000303|PubMed:22535423};
DE AltName: Full=MPK3/6-targeted VQ-motif-containing protein 4 {ECO:0000303|PubMed:24750137};
GN Name=VQ19 {ECO:0000303|PubMed:22535423};
GN Synonyms=MVQ4 {ECO:0000303|PubMed:24750137};
GN OrderedLocusNames=At3g15300 {ECO:0000312|Araport:AT3G15300};
GN ORFNames=K7L4.10 {ECO:0000312|EMBL:BAB02159.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R.F., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=22535423; DOI=10.1104/pp.112.196816;
RA Cheng Y., Zhou Y., Yang Y., Chi Y.J., Zhou J., Chen J.Y., Wang F., Fan B.,
RA Shi K., Zhou Y.H., Yu J.Q., Chen Z.;
RT "Structural and functional analysis of VQ motif-containing proteins in
RT Arabidopsis as interacting proteins of WRKY transcription factors.";
RL Plant Physiol. 159:810-825(2012).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND PHOSPHORYLATION AT SER-59; SER-65;
RP SER-127; SER-141; SER-152; THR-155; THR-196 AND SER-212.
RX PubMed=24750137; DOI=10.1111/nph.12817;
RA Pecher P., Eschen-Lippold L., Herklotz S., Kuhle K., Naumann K., Bethke G.,
RA Uhrig J., Weyhe M., Scheel D., Lee J.;
RT "The Arabidopsis thaliana mitogen-activated protein kinases MPK3 and MPK6
RT target a subclass of 'VQ-motif'-containing proteins to regulate immune
RT responses.";
RL New Phytol. 203:592-606(2014).
CC -!- FUNCTION: May modulate WRKY transcription factor activities.
CC {ECO:0000250|UniProtKB:Q9M9F0}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9M9F0}.
CC -!- PTM: Phosphorylated on serine and threonine residues by MPK6.
CC {ECO:0000269|PubMed:24750137}.
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DR EMBL; AP000413; BAB02159.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75642.1; -; Genomic_DNA.
DR EMBL; BT010686; AAR20743.1; -; mRNA.
DR EMBL; BT011503; AAS00343.1; -; mRNA.
DR RefSeq; NP_188148.1; NM_112393.3.
DR AlphaFoldDB; Q9LDZ1; -.
DR STRING; 3702.AT3G15300.1; -.
DR iPTMnet; Q9LDZ1; -.
DR PaxDb; Q9LDZ1; -.
DR PRIDE; Q9LDZ1; -.
DR ProteomicsDB; 242779; -.
DR EnsemblPlants; AT3G15300.1; AT3G15300.1; AT3G15300.
DR GeneID; 820761; -.
DR Gramene; AT3G15300.1; AT3G15300.1; AT3G15300.
DR KEGG; ath:AT3G15300; -.
DR Araport; AT3G15300; -.
DR TAIR; locus:2087075; AT3G15300.
DR eggNOG; ENOG502RIDK; Eukaryota.
DR HOGENOM; CLU_069496_0_0_1; -.
DR InParanoid; Q9LDZ1; -.
DR OMA; MINTLMV; -.
DR OrthoDB; 1494333at2759; -.
DR PhylomeDB; Q9LDZ1; -.
DR PRO; PR:Q9LDZ1; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LDZ1; baseline and differential.
DR Genevisible; Q9LDZ1; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR008889; VQ.
DR InterPro; IPR039611; VQ_4/11/13/19/31/33.
DR PANTHER; PTHR33402; PTHR33402; 1.
DR Pfam; PF05678; VQ; 1.
PE 1: Evidence at protein level;
KW Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..219
FT /note="VQ motif-containing protein 19"
FT /id="PRO_0000432316"
FT REGION 52..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 156..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 47..56
FT /note="VQ"
FT /evidence="ECO:0000305"
FT MOD_RES 59
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 65
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 127
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 131
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5M750"
FT MOD_RES 139
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9FHZ3"
FT MOD_RES 141
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 152
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 155
FT /note="Phosphothreonine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 192
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5M750"
FT MOD_RES 195
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9FHZ3"
FT MOD_RES 196
FT /note="Phosphothreonine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 211
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:O23660"
FT MOD_RES 212
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:24750137"
FT MOD_RES 216
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:O23660"
SQ SEQUENCE 219 AA; 23662 MW; 3ABE95C8EA20B5CC CRC64;
MEISTNPPSS SSSSVSSSII NGSLHHHIIT RSDHYPTTFV QADSSSFKQV VQMLTGSSSP
RSPDSPRPPT TPSGKGNFVI PPIKTAQPKK HSGNKLYERR SHGGFNNNLK NSLMINTLMI
GGGGAGSPRF SPRNQEILSP SCLDFPKLAL NSPVTPLKQG TNGNEGDPFD KMSPLSEEER
GIADKGYYLH RSPISTPRDS EPQLLPLFPV TSPRLSPEM
