ID   VR2B_BPT4               Reviewed;         312 AA.
AC   P03691;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 3.
DT   23-FEB-2022, entry version 101.
DE   RecName: Full=Protein rIIB;
GN   Name=rIIB;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-146.
RX   PubMed=6273585; DOI=10.1016/0022-2836(81)90477-0;
RA   Pribnow D., Sigurdson D.C., Gold L., Singer B.S., Napoli C., Brosius J.,
RA   Dull T.J., Noller H.F.;
RT   "rII cistrons of bacteriophage T4. DNA sequence around the intercistronic
RT   divide and positions of genetic landmarks.";
RL   J. Mol. Biol. 149:337-376(1981).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-47.
RX   PubMed=3806675; DOI=10.1016/0022-2836(86)90448-1;
RA   Ripley L.S., Clark A., de Boer J.G.;
RT   "Spectrum of spontaneous frameshift mutations. Sequences of bacteriophage
RT   T4 rII gene frameshifts.";
RL   J. Mol. Biol. 191:601-613(1986).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-33.
RX   PubMed=2379817; DOI=10.1093/genetics/125.2.237;
RA   Daegelen P., Brody E.;
RT   "The rIIA gene of bacteriophage T4. I. Its DNA sequence and discovery of a
RT   new open reading frame between genes 60 and rIIA.";
RL   Genetics 125:237-248(1990).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 146-312.
RX   PubMed=3020513;
RA   Huang W.M.;
RT   "The 52-protein subunit of T4 DNA topoisomerase is homologous to the gyrA-
RT   protein of gyrase.";
RL   Nucleic Acids Res. 14:7379-7390(1986).
CC   -!- FUNCTION: Transcribed prior to replication. This protein form parts of
CC       the replication complex and has DNA-binding properties.
CC   -!- SUBCELLULAR LOCATION: Host cell inner membrane. Note=On the inner
CC       membrane of the host shortly after infection.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF158101; AAD42649.1; -; Genomic_DNA.
DR   EMBL; M29623; AAA32532.1; -; Genomic_DNA.
DR   EMBL; X04376; CAA27958.1; -; Genomic_DNA.
DR   EMBL; X52686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; D16359; BAA23635.1; -; Genomic_DNA.
DR   PIR; S52614; Z2BPB4.
DR   RefSeq; NP_049889.1; NC_000866.4.
DR   GeneID; 1258618; -.
DR   KEGG; vg:1258618; -.
DR   Proteomes; UP000009087; Genome.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   DNA replication; DNA-binding; Early protein; Host cell inner membrane;
KW   Host cell membrane; Host membrane; Membrane; Reference proteome.
FT   CHAIN           1..312
FT                   /note="Protein rIIB"
FT                   /id="PRO_0000165071"
SQ   SEQUENCE   312 AA;  35541 MW;  9B3A55C6E8FA9818 CRC64;
     MYNIKCLTKN EQAEIVKLYS SGNYTQQELA DWQGVSVDTI RRVLKNAEEA KRPKVTISGD
     ITVKVNSDAV IAPVAKSDII WNASKKFISI TVDGVTYNAT PNTHSNFQEI LNLLVADKLE
     EAAQKINVRR AVEKYISGDV RIEGGSLFYQ NIELRSGLVD RILDSMEKGE NFEFYFPFLE
     NLLENPSQKA VSRLFDFLVA NDIEITEDGY FYAWKVVRSN YFDCHSNTFD NSPGKVVKMP
     RTRVNDDDTQ TCSRGLHVCS KSYIRHFGSS TSRVVKVKVH PRDVVSIPID YNDAKMRTCQ
     YEVVEDVTEQ FK