ID   VRAA_STAES              Reviewed;         411 AA.
AC   Q8CQ67;
DT   25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Putative long chain fatty acid-CoA ligase VraA;
DE            EC=6.2.1.-;
DE   AltName: Full=Acyl-CoA synthetase;
GN   Name=vraA; OrderedLocusNames=SE_0344;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       {ECO:0000305}.
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DR   EMBL; AE015929; AAO03941.1; -; Genomic_DNA.
DR   RefSeq; NP_763899.1; NC_004461.1.
DR   RefSeq; WP_011082603.1; NZ_WBME01000045.1.
DR   AlphaFoldDB; Q8CQ67; -.
DR   SMR; Q8CQ67; -.
DR   STRING; 176280.SE_0344; -.
DR   EnsemblBacteria; AAO03941; AAO03941; SE_0344.
DR   KEGG; sep:SE_0344; -.
DR   PATRIC; fig|176280.10.peg.317; -.
DR   eggNOG; COG0318; Bacteria.
DR   HOGENOM; CLU_000022_59_0_9; -.
DR   OMA; WFESVCK; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; -; 1.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig.
DR   InterPro; IPR042099; ANL_N_sf.
DR   Pfam; PF00501; AMP-binding; 2.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   3: Inferred from homology;
KW   Fatty acid metabolism; Ligase; Lipid metabolism.
FT   CHAIN           1..411
FT                   /note="Putative long chain fatty acid-CoA ligase VraA"
FT                   /id="PRO_0000193197"
SQ   SEQUENCE   411 AA;  46930 MW;  42E8B4C115DCB3DE CRC64;
     MKKIMEYLQH YINQYPHRLA LVFEDRHLTY GELSKEIYQA SMRYKEVKLN KKVGLMDEHP
     VNNIINYFAV HQRGGIPCIF NHQWSNERIY QLVKSYDIQW LIKDNHLTSN HDNSIYNDEV
     IPRNVIHIGF TSGTTGLPKA FYRNEHSWIV SFKENEKLLQ HCEETIVAPG PLSHSLSLYA
     CIYALSTGKT FIGQKNFNPL SLMRLINQLN KATAIFVVPT MVQQLISTQR HCSSIKSILS
     SGAKLTLQQF QQIRNLYPQA NLIEFFGTSE ASFISYNFNQ SSPANSVGKL FPHVETRLLN
     QDDDAVGLLA VRSEMVFSGY VGQSNQEGAW IKTGDFAYIK NQHLFLVGRE SDRIIVGGIN
     VYPTAIESLI MDIEGIDEAL VIGIPHAKFG EIAILLYSGK VQLNYRQIKF F