VRAC_STAA1
ID VRAC_STAA1 Reviewed; 121 AA.
AC Q9KWK3; A7WZ16;
DT 25-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=Protein VraC;
GN Name=vraC; OrderedLocusNames=SAHV_0575;
OS Staphylococcus aureus (strain Mu3 / ATCC 700698).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=418127;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VANCOMYCIN RESISTANCE.
RX PubMed=10708580; DOI=10.1006/bbrc.2000.2277;
RA Kuroda M., Kuwahara-Arai K., Hiramatsu K.;
RT "Identification of the up- and down-regulated genes in vancomycin-resistant
RT Staphylococcus aureus strains Mu3 and Mu50 by cDNA differential
RT hybridization method.";
RL Biochem. Biophys. Res. Commun. 269:485-490(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mu3 / ATCC 700698;
RX PubMed=17954695; DOI=10.1128/aac.00534-07;
RA Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K.;
RT "Mutated response regulator graR is responsible for phenotypic conversion
RT of Staphylococcus aureus from heterogeneous vancomycin-intermediate
RT resistance to vancomycin-intermediate resistance.";
RL Antimicrob. Agents Chemother. 52:45-53(2008).
CC -!- MISCELLANEOUS: May contribute to vancomycin resistance.
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DR EMBL; AB035449; BAB03329.1; -; Genomic_DNA.
DR EMBL; AP009324; BAF77458.1; -; Genomic_DNA.
DR PIR; C89826; C89826.
DR RefSeq; WP_001165058.1; NZ_CTYB01000020.1.
DR AlphaFoldDB; Q9KWK3; -.
DR SMR; Q9KWK3; -.
DR KEGG; saw:SAHV_0575; -.
DR HOGENOM; CLU_2195295_0_0_9; -.
DR OMA; MCAKLWP; -.
DR InterPro; IPR016994; UCP032370_VraC.
DR PIRSF; PIRSF032370; UCP032370_VraC; 1.
PE 4: Predicted;
FT CHAIN 1..121
FT /note="Protein VraC"
FT /id="PRO_0000065915"
SQ SEQUENCE 121 AA; 14187 MW; 292F3EA8F1065F7C CRC64;
MQHYLLDSNQ RLNVSFSKDS VAAYYQCFNQ PYRKEVPPLM CASLWPKFDL FKKYANSELI
LTKSAINQTQ KIEVDTIYVG HLEDIECRQT RNITRYTMAL TLTKNDQHVI TVTQTFIKAM
K