ID   VRPP_LAMBD              Reviewed;         233 AA.
AC   P03689;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   12-AUG-2020, entry version 67.
DE   RecName: Full=Replication protein P;
GN   Name=P;
OS   Escherichia phage lambda (Bacteriophage lambda).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Lambdavirus.
OX   NCBI_TaxID=10710;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=6221115; DOI=10.1016/0022-2836(82)90546-0;
RA   Sanger F., Coulson A.R., Hong G.F., Hill D.F., Petersen G.B.;
RT   "Nucleotide sequence of bacteriophage lambda DNA.";
RL   J. Mol. Biol. 162:729-773(1982).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DVO21;
RA   Schwarz E., Scherer G., Hobom G., Koessel H.;
RT   "The primary structure of the phage lambda P gene completes the nucleotide
RT   sequence of the plasmid lambda dvh93.";
RL   Biochem. Int. 1:386-394(1980).
CC   -!- FUNCTION: Replication protein P is necessary for the bidirectional
CC       replication of lambda DNA. It interacts with the ori (origin of
CC       replication) region of the genome during the initiation of replication.
CC   -!- SIMILARITY: Belongs to the phage P protein family. {ECO:0000305}.
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DR   EMBL; J02459; AAA96585.1; -; Genomic_DNA.
DR   PIR; G94614; PQBPL.
DR   RefSeq; NP_040632.1; NC_001416.1.
DR   PDB; 6BBM; EM; 4.10 A; V/W/X/Y/Z=1-107.
DR   PDBsum; 6BBM; -.
DR   SMR; P03689; -.
DR   IntAct; P03689; 8.
DR   GeneID; 2703495; -.
DR   KEGG; vg:2703495; -.
DR   Proteomes; UP000001711; Genome.
DR   GO; GO:0039686; P:bidirectional double-stranded viral DNA replication; IDA:UniProtKB.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   InterPro; IPR009731; Phage_lambda_P.
DR   Pfam; PF06992; Phage_lambda_P; 1.
PE   1: Evidence at protein level;
KW   3D-structure; DNA replication; Reference proteome.
FT   CHAIN           1..233
FT                   /note="Replication protein P"
FT                   /id="PRO_0000077704"
SQ   SEQUENCE   233 AA;  26518 MW;  31342D4D356CB33C CRC64;
     MKNIAAQMVN FDREQMRRIA NNMPEQYDEK PQVQQVAQII NGVFSQLLAT FPASLANRDQ
     NEVNEIRRQW VLAFRENGIT TMEQVNAGMR VARRQNRPFL PSPGQFVAWC REEASVTAGL
     PNVSELVDMV YEYCRKRGLY PDAESYPWKS NAHYWLVTNL YQNMRANALT DAELRRKAAD
     ELVHMTARIN RGEAIPEPVK QLPVMGGRPL NRAQALAKIA EIKAKFGLKG ASV