ID   VRTN_MOUSE              Reviewed;         740 AA.
AC   Q3SYK4;
DT   08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Vertnin;
GN   Name=Vrtn;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Oocyte;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the vertnin family. {ECO:0000305}.
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DR   EMBL; CH466590; EDL02817.1; -; Genomic_DNA.
DR   EMBL; BC103771; AAI03772.1; -; mRNA.
DR   CCDS; CCDS26048.1; -.
DR   RefSeq; NP_001028948.1; NM_001033776.2.
DR   RefSeq; NP_001162060.1; NM_001168588.1.
DR   RefSeq; NP_001162061.1; NM_001168589.2.
DR   AlphaFoldDB; Q3SYK4; -.
DR   BioGRID; 240749; 2.
DR   IntAct; Q3SYK4; 1.
DR   STRING; 10090.ENSMUSP00000132050; -.
DR   PhosphoSitePlus; Q3SYK4; -.
DR   PaxDb; Q3SYK4; -.
DR   PeptideAtlas; Q3SYK4; -.
DR   PRIDE; Q3SYK4; -.
DR   Antibodypedia; 7; 48 antibodies from 15 providers.
DR   Ensembl; ENSMUST00000095551; ENSMUSP00000093207; ENSMUSG00000071235.
DR   Ensembl; ENSMUST00000166772; ENSMUSP00000128808; ENSMUSG00000071235.
DR   Ensembl; ENSMUST00000167227; ENSMUSP00000132050; ENSMUSG00000071235.
DR   GeneID; 432677; -.
DR   KEGG; mmu:432677; -.
DR   UCSC; uc007ofq.1; mouse.
DR   CTD; 55237; -.
DR   MGI; MGI:3588197; Vrtn.
DR   VEuPathDB; HostDB:ENSMUSG00000071235; -.
DR   eggNOG; ENOG502SC23; Eukaryota.
DR   GeneTree; ENSGT00390000007874; -.
DR   HOGENOM; CLU_429970_0_0_1; -.
DR   InParanoid; Q3SYK4; -.
DR   OMA; VLQRNIY; -.
DR   OrthoDB; 570582at2759; -.
DR   PhylomeDB; Q3SYK4; -.
DR   TreeFam; TF332015; -.
DR   BioGRID-ORCS; 432677; 5 hits in 73 CRISPR screens.
DR   ChiTaRS; Vrtn; mouse.
DR   PRO; PR:Q3SYK4; -.
DR   Proteomes; UP000000589; Chromosome 12.
DR   RNAct; Q3SYK4; protein.
DR   Bgee; ENSMUSG00000071235; Expressed in animal zygote and 11 other tissues.
DR   ExpressionAtlas; Q3SYK4; baseline and differential.
DR   Genevisible; Q3SYK4; MM.
DR   GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR038822; Vertnin-like.
DR   PANTHER; PTHR16081; PTHR16081; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..740
FT                   /note="Vertnin"
FT                   /id="PRO_0000404600"
FT   REGION          485..506
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          560..616
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          653..673
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        574..606
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        653..671
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   740 AA;  83135 MW;  69E1C25A0AB0AEF4 CRC64;
     MTSRDQLVQQ VLRDLQEAVE SEGLEGLIGA ALEAKQVLSS FTLPICQKGG PGAQVLEVDS
     VALSLYPEDA PRNMLPLVCK GEGSLLFEAT SLLLWGHTGL SLELRARTVV EMLLHRHYYL
     QGMIDSKVML QAVRYSLCSE ESPEMTNLSF ATLEAIFDAD VKATCFPTSF SNVWHLYALA
     SILECNIYSI YPMRNIKIRP YFNRVIMPRC STHVTSMLHI MWAGQPLTSH LFRHQYFAPV
     VGLEEVEADC TASLNPVPPN LGPLLPPAKT LELLNREPGL SYSHLCDRIS ITKSTFYRWR
     RQTQEHRQKV ATRFSAKHFL QDSFHRGGFV PLQQFLQRFP EISRSTYYAW KHELLGSGAN
     SALGPATPSR EALAVPEVER PPGKKAAEEV GCSSLAAAML SPPSMILMQR AKSFLEYCIS
     LNKLVPYRCF KCRFPGISRS TYYNWRRKAL RRTPSFKLSQ AAFETAESLQ PTDVGKETPF
     SLKREAGEEE TGKAGSGAPL TSRGLISPKM PLSRWQRRLR RAARKQVLNG HLPFCRFRLR
     YPSLLPSTFW VWKSLSRRSP GMQIPSLSQR RQKPQGRQKP EGRQKPEEQQ KPEGRQKPEG
     RQKPVEPQAM EADQNVPAMV VPPAETLPVA TSPEDVPGGP SREGNIIQEA AMTQSQPHSG
     SLPSQTLAEA PGGSDGQVLV MDMLTTTRFK AQAKLFLQKR FQSKTFPSYK EFQALFPLTA
     RSTYYMWKRA LYEGLTLIDG