VSH7_DICDI
ID VSH7_DICDI Reviewed; 104 AA.
AC P14327; Q556W5; Q558A1; Q86AJ3;
DT 01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 2.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Vegetative-specific protein H7;
GN Name=cinD-1; Synonyms=H7; ORFNames=DDB_G0273061;
GN and
GN Name=cinD-2; Synonyms=H7; ORFNames=DDB_G0273775;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=AX3;
RA Singleton C.K., Manning S.S., Ken R.;
RL Submitted (MAY-1989) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- DEVELOPMENTAL STAGE: This protein is expressed in growing cells and
CC deactivated upon the initiation of development.
CC -!- CAUTION: The gene for this protein is duplicated in strains AX3 and
CC AX4. These strains contain a duplication of a segment of 750 kb of
CC chromosome 2 compared to the corresponding sequence in strain AX2.
CC {ECO:0000305}.
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DR EMBL; X15385; CAA33444.1; -; mRNA.
DR EMBL; AAFI02000011; EAL70578.2; -; Genomic_DNA.
DR EMBL; AAFI02000009; EAL70748.1; -; Genomic_DNA.
DR PIR; S07568; S07568.
DR RefSeq; XP_644504.2; XM_639412.2.
DR RefSeq; XP_644746.1; XM_639654.1.
DR AlphaFoldDB; P14327; -.
DR SMR; P14327; -.
DR STRING; 44689.DDB0191304; -.
DR PaxDb; P14327; -.
DR EnsemblProtists; EAL70578; EAL70578; DDB_G0273775.
DR EnsemblProtists; EAL70748; EAL70748; DDB_G0273061.
DR GeneID; 8618846; -.
DR GeneID; 8619130; -.
DR KEGG; ddi:DDB_G0273061; -.
DR KEGG; ddi:DDB_G0273775; -.
DR dictyBase; DDB_G0273061; cinD-1.
DR dictyBase; DDB_G0273775; cinD-2.
DR eggNOG; KOG3398; Eukaryota.
DR HOGENOM; CLU_112609_0_2_1; -.
DR InParanoid; P14327; -.
DR OMA; DLASKIC; -.
DR PhylomeDB; P14327; -.
DR PRO; PR:P14327; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003713; F:transcription coactivator activity; ISS:dictyBase.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; ISS:dictyBase.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; -; 1.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR Pfam; PF01381; HTH_3; 1.
DR SMART; SM00530; HTH_XRE; 1.
DR SUPFAM; SSF47413; SSF47413; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Reference proteome.
FT CHAIN 1..104
FT /note="Vegetative-specific protein H7"
FT /id="PRO_0000149745"
FT DOMAIN 43..97
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT DNA_BIND 54..73
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT CONFLICT 24
FT /note="V -> A (in Ref. 1; CAA33444)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 104 AA; 11354 MW; AB529688028AD25A CRC64;
MDVQTKYGAG QNKVLGGANQ KKIVESEEDI ALPELNPSVP QAIQRARNAL KMTQKELAFK
INERPGVINE YESGSAIPSQ AVLSKLEKAL NVKLRGKEIG KPLK