VSP55_ARATH
ID VSP55_ARATH Reviewed; 140 AA.
AC Q9AST6; Q8LCQ6; Q9LQL7;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Vacuolar protein sorting-associated protein 55 homolog;
GN OrderedLocusNames=At1g32410; ORFNames=F5D14.32;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in endosomal protein transport. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endosome membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the OB-RGRP/VPS55 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF81338.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At1g32410 and At1g32415.; Evidence={ECO:0000305};
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DR EMBL; AC007767; AAF81338.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE31479.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31480.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31481.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31482.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31483.1; -; Genomic_DNA.
DR EMBL; AF361848; AAK32860.1; -; mRNA.
DR EMBL; AY066053; AAL47420.1; -; mRNA.
DR EMBL; AK176917; BAD44680.1; -; mRNA.
DR EMBL; AK230417; BAF02215.1; -; mRNA.
DR EMBL; AY086458; AAM63461.1; -; mRNA.
DR PIR; B86449; B86449.
DR RefSeq; NP_001077643.1; NM_001084174.1.
DR RefSeq; NP_001077644.1; NM_001084175.1.
DR RefSeq; NP_001077645.1; NM_001084176.1.
DR RefSeq; NP_564400.1; NM_102975.1.
DR RefSeq; NP_849741.1; NM_179410.4.
DR AlphaFoldDB; Q9AST6; -.
DR BioGRID; 25368; 11.
DR IntAct; Q9AST6; 13.
DR STRING; 3702.AT1G32410.3; -.
DR PaxDb; Q9AST6; -.
DR PRIDE; Q9AST6; -.
DR ProteomicsDB; 242649; -.
DR EnsemblPlants; AT1G32410.1; AT1G32410.1; AT1G32410.
DR EnsemblPlants; AT1G32410.2; AT1G32410.2; AT1G32410.
DR EnsemblPlants; AT1G32410.3; AT1G32410.3; AT1G32410.
DR EnsemblPlants; AT1G32410.4; AT1G32410.4; AT1G32410.
DR EnsemblPlants; AT1G32410.5; AT1G32410.5; AT1G32410.
DR GeneID; 840134; -.
DR Gramene; AT1G32410.1; AT1G32410.1; AT1G32410.
DR Gramene; AT1G32410.2; AT1G32410.2; AT1G32410.
DR Gramene; AT1G32410.3; AT1G32410.3; AT1G32410.
DR Gramene; AT1G32410.4; AT1G32410.4; AT1G32410.
DR Gramene; AT1G32410.5; AT1G32410.5; AT1G32410.
DR KEGG; ath:AT1G32410; -.
DR Araport; AT1G32410; -.
DR TAIR; locus:2033729; AT1G32410.
DR eggNOG; KOG2174; Eukaryota.
DR HOGENOM; CLU_134810_1_0_1; -.
DR InParanoid; Q9AST6; -.
DR OMA; HSAVITW; -.
DR OrthoDB; 1642378at2759; -.
DR PhylomeDB; Q9AST6; -.
DR PRO; PR:Q9AST6; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9AST6; baseline and differential.
DR Genevisible; Q9AST6; AT.
DR GO; GO:0005768; C:endosome; IBA:GO_Central.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IBA:GO_Central.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR007262; Vps55/LEPROT.
DR PANTHER; PTHR12050; PTHR12050; 1.
DR Pfam; PF04133; Vps55; 1.
PE 2: Evidence at transcript level;
KW Endosome; Membrane; Protein transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..140
FT /note="Vacuolar protein sorting-associated protein 55
FT homolog"
FT /id="PRO_0000342739"
FT TOPO_DOM 1..16
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 38..40
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 62..75
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 76..98
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 99..108
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 130..140
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CONFLICT 117
FT /note="V -> L (in Ref. 5; AAM63461)"
FT /evidence="ECO:0000305"
FT CONFLICT 134
FT /note="D -> E (in Ref. 5; AAM63461)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 140 AA; 15025 MW; A9B60C5B65EA2506 CRC64;
MADVPGYLRT CLDMGKIAFL AILVSTGIVL QILACALFNN WWPMLSVIMY VLLPMPLLFF
GGSDSTSLFN ESDNSWINAA KFLTGASAVG SVAIPSILKH AGLIGWGALA LDLSSYVVFL
VAILGYICIG DASDNYYSYI
