VSR_CLV
ID VSR_CLV Reviewed; 101 AA.
AC P22625;
DT 01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1991, sequence version 1.
DT 03-AUG-2022, entry version 52.
DE RecName: Full=RNA silencing suppressor;
DE AltName: Full=11.6 kDa protein;
DE AltName: Full=Putative nucleic acid-binding protein;
GN Name=TUC;
OS Carnation latent virus (CLV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Tymovirales; Betaflexiviridae; Quinvirinae; Carlavirus.
OX NCBI_TaxID=12164;
OH NCBI_TaxID=3570; Dianthus caryophyllus (Carnation) (Clove pink).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2235495; DOI=10.1093/nar/18.20.6127;
RA Taylor M.T.M., Brunt A.A., Coutts R.H.A.;
RT "Conservation of the 3' terminal nucleotide sequence in five
RT carlaviruses.";
RL Nucleic Acids Res. 18:6127-6127(1990).
CC -!- FUNCTION: Suppressor of viral-induced RNA silencing. The potential
CC mechanism of action is based on sequestering siRNAs (By similarity).
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the carlaviruses nucleic acid-binding protein
CC family. {ECO:0000305}.
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DR EMBL; X55897; CAA39386.1; -; Genomic_RNA.
DR PIR; S12170; S12170.
DR SMR; P22625; -.
DR PRIDE; P22625; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR InterPro; IPR002568; Carla-bd.
DR Pfam; PF01623; Carla_C4; 1.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Suppressor of RNA silencing; Zinc; Zinc-finger.
FT CHAIN 1..101
FT /note="RNA silencing suppressor"
FT /id="PRO_0000222652"
FT ZN_FING 57..78
FT /note="C4-type"
FT /evidence="ECO:0000255"
FT REGION 47..50
FT /note="Basic"
FT /evidence="ECO:0000250"
SQ SEQUENCE 101 AA; 11627 MW; 58DF36C3A14A5091 CRC64;
MRERKLRKQL EDLFKRFASV QHGHSDCINI IIAKIKSDQP GESKYARRRR AKSIARCPRC
ARVSPGFYFT TRCDGKTCRP GLSARPDLLE FIGIDLCVRS K