ID   VSR_HELVS               Reviewed;         110 AA.
AC   Q00572;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   23-FEB-2022, entry version 46.
DE   RecName: Full=RNA silencing suppressor;
DE   AltName: Full=12.6 kDa protein;
DE   AltName: Full=Putative nucleic acid-binding protein;
OS   Helenium virus S (HelVS).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Betaflexiviridae; Quinvirinae; Carlavirus.
OX   NCBI_TaxID=12171;
OH   NCBI_TaxID=289417; Helenium amarum.
OH   NCBI_TaxID=35939; Impatiens.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2391504; DOI=10.1099/0022-1317-71-8-1877;
RA   Foster G.D., Millar A.W., Meehan B.M., Mills P.R.;
RT   "Nucleotide sequence of the 3'-terminal region of Helenium virus S RNA.";
RL   J. Gen. Virol. 71:1877-1880(1990).
CC   -!- FUNCTION: Suppressor of viral-induced RNA silencing. The potential
CC       mechanism of action is based on sequestering siRNAs (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the carlaviruses nucleic acid-binding protein
CC       family. {ECO:0000305}.
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DR   EMBL; D10454; BAA01249.1; -; Genomic_RNA.
DR   Proteomes; UP000242950; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR002568; Carla-bd.
DR   Pfam; PF01623; Carla_C4; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Suppressor of RNA silencing; Zinc; Zinc-finger.
FT   CHAIN           1..110
FT                   /note="RNA silencing suppressor"
FT                   /id="PRO_0000222651"
FT   ZN_FING         60..81
FT                   /note="C4-type"
FT                   /evidence="ECO:0000255"
FT   REGION          50..53
FT                   /note="Basic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   110 AA;  12663 MW;  E06989FA8FAC01CE CRC64;
     MDKRNKANVV LSLCSMFASR GNCIPIPIVF NIYMRAFPKL VGRGTSTYAR RRRARSILRC
     ERCYRVYPPL PFSKKCDNRT CVPGISYNIK VADFIKWGVT EVIPHPGFNF