ID   VSR_POPMV               Reviewed;         123 AA.
AC   Q02123;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 2.
DT   07-OCT-2020, entry version 49.
DE   RecName: Full=RNA silencing suppressor;
DE   AltName: Full=14 kDa protein;
DE   AltName: Full=Putative nucleic acid-binding protein;
OS   Poplar mosaic virus (isolate ATCC Pv275) (PMV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Betaflexiviridae; Quinvirinae; Carlavirus.
OX   NCBI_TaxID=31709;
OH   NCBI_TaxID=73824; Populus balsamifera (Balsam poplar).
OH   NCBI_TaxID=3696; Populus deltoides (Eastern poplar) (Eastern cottonwood).
OH   NCBI_TaxID=75703; Populus maximowiczii (Japanese poplar).
OH   NCBI_TaxID=3691; Populus nigra (Lombardy poplar).
OH   NCBI_TaxID=3694; Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=1629709; DOI=10.1099/0022-1317-73-7-1887;
RA   Henderson J., Gibbs M.J., Edwards M.-L., Clarke V.A., Gardner K.A.,
RA   Cooper J.I.;
RT   "Partial nucleotide sequence of poplar mosaic virus RNA confirms its
RT   classification as a carlavirus.";
RL   J. Gen. Virol. 73:1887-1890(1992).
RN   [2]
RP   SEQUENCE REVISION TO C-TERMINUS.
RX   PubMed=15664047; DOI=10.1016/j.jviromet.2004.10.007;
RA   Naylor M., Reeves J., Cooper J.I., Edwards M.-L., Wang H.;
RT   "Construction and properties of a gene-silencing vector based on Poplar
RT   mosaic virus (genus Carlavirus).";
RL   J. Virol. Methods 124:27-36(2005).
CC   -!- FUNCTION: Suppressor of viral-induced RNA silencing. The potential
CC       mechanism of action is based on sequestering siRNAs (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the carlaviruses nucleic acid-binding protein
CC       family. {ECO:0000305}.
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DR   EMBL; X65102; CAA46227.2; -; Genomic_RNA.
DR   PIR; JQ1646; JQ1646.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR002568; Carla-bd.
DR   Pfam; PF01623; Carla_C4; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Suppressor of RNA silencing; Zinc; Zinc-finger.
FT   CHAIN           1..123
FT                   /note="RNA silencing suppressor"
FT                   /id="PRO_0000222654"
FT   ZN_FING         62..83
FT                   /note="C4-type"
FT                   /evidence="ECO:0000255"
FT   REGION          52..55
FT                   /note="Basic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   123 AA;  14416 MW;  C88AEB7E1EDA12EC CRC64;
     MVNMRKVLAL MQVFRERYDH KCDFNFCDIA VSIVCRSELD FINEPGLSNY AKRRRARRLG
     RCVRCFRVNP GFYFTKRCDG ITCVPGISWN YDVEDYIKRG RVTGDRETPS TFHGYGYPVG
     HKT