ID   VSR_PVSP                Reviewed;          93 AA.
AC   P16654;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   23-FEB-2022, entry version 49.
DE   RecName: Full=RNA silencing suppressor;
DE   AltName: Full=10.7 kDa protein;
DE   AltName: Full=Putative nucleic acid-binding protein;
OS   Potato virus S (strain Peruvian).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Tymovirales; Betaflexiviridae; Quinvirinae; Carlavirus.
OX   NCBI_TaxID=12170;
OH   NCBI_TaxID=4113; Solanum tuberosum (Potato).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=2732711; DOI=10.1099/0022-1317-70-5-1053;
RA   Mackenzie D.J., Tremaine J.H., Stace-Smith R.;
RT   "Organization and interviral homologies of the 3'-terminal portion of
RT   potato virus S RNA.";
RL   J. Gen. Virol. 70:1053-1063(1989).
CC   -!- FUNCTION: Suppressor of viral-induced RNA silencing. The potential
CC       mechanism of action is based on sequestering siRNAs (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the carlaviruses nucleic acid-binding protein
CC       family. {ECO:0000305}.
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DR   EMBL; D00461; BAA00356.1; -; Genomic_RNA.
DR   PIR; JA0128; JA0128.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR002568; Carla-bd.
DR   Pfam; PF01623; Carla_C4; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Suppressor of RNA silencing; Zinc; Zinc-finger.
FT   CHAIN           1..93
FT                   /note="RNA silencing suppressor"
FT                   /id="PRO_0000222655"
FT   ZN_FING         54..69
FT                   /note="C4-type"
FT                   /evidence="ECO:0000255"
FT   REGION          44..47
FT                   /note="Basic"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   93 AA;  10751 MW;  D2E9AFB3A473004C CRC64;
     MKAERLEMLL LCVYRLGYIL PVDVCIKIIS VAQVSVQGRS TYSCKRRARS IGRCWRCYRV
     YPPVCNSKCD NRTCRPGISP NFKVVTFIRG WSN