ID   VSR_RDVF                Reviewed;         353 AA.
AC   Q85434; Q85441;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   12-AUG-2020, entry version 52.
DE   RecName: Full=Suppressor of RNA-mediated gene silencing;
DE   AltName: Full=Non-structural protein 10;
DE            Short=Pns10;
OS   Rice dwarf virus (isolate Fujian) (RDV).
OC   Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes;
OC   Reovirales; Reoviridae; Sedoreovirinae; Phytoreovirus.
OX   NCBI_TaxID=142804;
OH   NCBI_TaxID=114194; Alopecurus aequalis.
OH   NCBI_TaxID=90397; Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli).
OH   NCBI_TaxID=94400; Nephotettix cincticeps (Green rice leafhopper) (Selenocephalus cincticeps).
OH   NCBI_TaxID=4530; Oryza sativa (Rice).
OH   NCBI_TaxID=147271; Paspalum.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Chu R., Zhang X., Pan N., Chen Z.;
RT   "Molecular cloning and sequencing of rice dwarf virus segment 10.";
RL   Chin. J. Bot. 35:115-120(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Chu R., Zhang X., Pan N., Chen Z.;
RT   "The cDNA cloning and nucleotide sequence of the gene encoding
RT   nonstructural protein of rice dwarf virus genome segment 10.";
RL   Acta Bot. Sin. 35:115-120(1993).
RN   [3]
RP   FUNCTION.
RX   PubMed=16189004; DOI=10.1128/jvi.79.20.13018-13027.2005;
RA   Cao X., Zhou P., Zhang X., Zhu S., Zhong X., Xiao Q., Ding B., Li Y.;
RT   "Identification of an RNA silencing suppressor from a plant double-stranded
RT   RNA virus.";
RL   J. Virol. 79:13018-13027(2005).
RN   [4]
RP   FUNCTION.
RX   PubMed=20545438; DOI=10.4149/av_2010_02_99;
RA   Zhou P., Ren B., Zhang X.M., Wang Y., Wei C.H., Li Y.;
RT   "Stable expression of rice dwarf virus Pns10 suppresses the post-
RT   transcriptional gene silencing in transgenic Nicotiana benthamiana
RT   plants.";
RL   Acta Virol. 54:99-104(2010).
CC   -!- FUNCTION: Suppressor of RNA-mediated gene silencing, also known as
CC       post-transcriptional gene silencing (PTGS), a mechanism of plant viral
CC       defense that limits the accumulation of viral RNAs.
CC       {ECO:0000269|PubMed:16189004, ECO:0000269|PubMed:20545438}.
CC   -!- SIMILARITY: Belongs to the phytoreovirus non-structural protein 10
CC       family. {ECO:0000305}.
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DR   EMBL; U36567; AAA88766.1; -; mRNA.
DR   EMBL; U25671; AAA70094.1; -; Genomic_RNA.
DR   Proteomes; UP000002239; Genome.
DR   InterPro; IPR008777; Phytoreo_Pns.
DR   Pfam; PF05451; Phytoreo_Pns; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..353
FT                   /note="Suppressor of RNA-mediated gene silencing"
FT                   /id="PRO_0000222798"
FT   CONFLICT        159
FT                   /note="T -> I (in Ref. 1; AAA88766)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        320
FT                   /note="D -> H (in Ref. 1; AAA88766)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        328
FT                   /note="S -> Y (in Ref. 1; AAA88766)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        335
FT                   /note="A -> V (in Ref. 1; AAA88766)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   353 AA;  39247 MW;  9F6D51F539758413 CRC64;
     MEVDTATFVR LHHELLCAHE GPSIISKFDA IKKVKLGTLA NQSGGANNIT EAFFDKLRNF
     ERKSEAYLAS DLAERELTRD THKAIVFVTK SVLLGGKSLK DLLPYGVIVC AFIFIPETAS
     VLDNVRVMIG NQKRPLTVAL IKYMAKSLNC DLVGDSYDTF YYCNSSAYGK NLISVSENDF
     SNPQRALLSV GDLCYQAARS IHVAAANYIR IFDRMPPGFQ PSKHLFRIIG VLDMETLKTM
     VTSNIAREPG MFSHDNVKDV LHRTGVFSPN HHFSAVILWR GWASTYAYMF NQEQLNMLSG
     TSGLAGDFGK YKLTYGSTFD EGVIHVQSQF VTPEAVRKRN IYPDLSALKG GSS