VSR_SBWMN
ID VSR_SBWMN Reviewed; 174 AA.
AC Q06392;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 23-FEB-2022, entry version 46.
DE RecName: Full=Suppressor of RNA silencing;
DE AltName: Full=19kD cysteine rich protein;
DE Short=P19;
OS Soil-borne wheat mosaic virus (strain United States/Nebraska/1981) (SBWMV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Martellivirales; Virgaviridae; Furovirus.
OX NCBI_TaxID=652673;
OH NCBI_TaxID=4513; Hordeum vulgare (Barley).
OH NCBI_TaxID=4564; Triticum.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=8317092; DOI=10.1006/viro.1993.1342;
RA Shirako Y., Wilson T.M.;
RT "Complete nucleotide sequence and organization of the bipartite RNA genome
RT of soil-borne wheat mosaic virus.";
RL Virology 195:16-32(1993).
RN [2]
RP FUNCTION.
RX PubMed=15740624; DOI=10.1186/1743-422x-2-18;
RA Te J., Melcher U., Howard A., Verchot-Lubicz J.;
RT "Soilborne wheat mosaic virus (SBWMV) 19K protein belongs to a class of
RT cysteine rich proteins that suppress RNA silencing.";
RL Virol. J. 2:18-18(2005).
CC -!- FUNCTION: Suppressor of RNA-mediated gene silencing, also known as
CC post-transcriptional gene silencing (PTGS), a mechanism of plant viral
CC defense that performs sequence-specific inhibition of viral mRNAs
CC expression. {ECO:0000269|PubMed:15740624}.
CC -!- SIMILARITY: Belongs to the virgaviridae suppressor of RNA silencing
CC family. {ECO:0000305}.
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DR EMBL; L07938; AAA48496.1; -; Genomic_RNA.
DR RefSeq; NP_049340.1; NC_002042.1.
DR SMR; Q06392; -.
DR GeneID; 991052; -.
DR KEGG; vg:991052; -.
DR Proteomes; UP000009270; Genome.
DR InterPro; IPR016567; Cys-rich_furovirus.
DR InterPro; IPR007609; Viral_P18.
DR Pfam; PF04521; Viral_P18; 1.
DR PIRSF; PIRSF010309; Cyc-rich_ssRNA; 1.
PE 3: Inferred from homology;
KW Coiled coil; Reference proteome; Suppressor of RNA silencing.
FT CHAIN 1..174
FT /note="Suppressor of RNA silencing"
FT /id="PRO_0000409451"
FT COILED 86..116
FT /evidence="ECO:0000255"
SQ SEQUENCE 174 AA; 18781 MW; 819ADCF867612416 CRC64;
MSTVGFHTCA SCVDGPKSIK CVSKYRISVY KTLGLDVVKC RLPADCGVNC GMPAAFVLEQ
GHPKLTMDGY CGEKHRGYVL SGAWRHAQLR SLNAELDTLE AREESLRAQI KALSAGDHCP
AVLAYVPKKL TKLKAEVHDV TGKKQVCITG LVDVMDSALV RLAPDSPPKK ISSL