ID   VSV4_DICDI              Reviewed;         160 AA.
AC   P14330; P14331; Q3LQX1; Q54V31;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 2.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Vegetative-specific protein V4;
GN   Name=lmcB; Synonyms=lmcA, V4; ORFNames=DDB_G0280533;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RC   STRAIN=AX3;
RX   PubMed=1312963; DOI=10.1016/0012-1606(92)90238-c;
RA   McPherson C.E., Singleton C.K.;
RT   "V4, a gene required for the transition from growth to development in
RT   Dictyostelium discoideum.";
RL   Dev. Biol. 150:231-242(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8345518; DOI=10.1006/jmbi.1993.1398;
RA   McPherson C.E., Singleton C.K.;
RT   "Nutrient-responsive promoter elements of the V4 gene of Dictyostelium
RT   discoideum.";
RL   J. Mol. Biol. 232:386-396(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Unknown. Its expression during growth is not required for
CC       growth but for the proper initiation of development, therefore playing
CC       a role in the transition from growth to development.
CC   -!- DEVELOPMENTAL STAGE: Only expressed during growth.
CC       {ECO:0000269|PubMed:1312963}.
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DR   EMBL; S89883; AAA08249.2; -; mRNA.
DR   EMBL; X15380; CAA33440.1; -; Genomic_DNA.
DR   EMBL; X15381; CAA33441.1; -; Genomic_DNA.
DR   EMBL; AAFI02000037; EAL67068.1; -; Genomic_DNA.
DR   PIR; S35649; S35649.
DR   RefSeq; XP_641100.1; XM_636008.1.
DR   AlphaFoldDB; P14330; -.
DR   STRING; 44689.DDB0215343; -.
DR   PaxDb; P14330; -.
DR   EnsemblProtists; EAL67068; EAL67068; DDB_G0280533.
DR   GeneID; 8622659; -.
DR   KEGG; ddi:DDB_G0280533; -.
DR   dictyBase; DDB_G0280533; lmcB.
DR   HOGENOM; CLU_1655429_0_0_1; -.
DR   PRO; PR:P14330; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.
DR   GO; GO:0010628; P:positive regulation of gene expression; IMP:dictyBase.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Developmental protein; Growth regulation; Reference proteome; Repeat.
FT   CHAIN           1..160
FT                   /note="Vegetative-specific protein V4"
FT                   /id="PRO_0000065932"
FT   REPEAT          151..153
FT                   /note="1"
FT   REPEAT          154..156
FT                   /note="2"
FT   REPEAT          157..159
FT                   /note="3"
FT   REGION          151..159
FT                   /note="3 X 3 AA tandem repeats of N-Q-[PG]"
SQ   SEQUENCE   160 AA;  17792 MW;  17B3B2005142D5A7 CRC64;
     MSSINPSLYN DNGVYCSKVI VTKAIKIRDL DQIPQTVLAL AATNNGANYD YASPNYITNA
     RKRFKARLNR NPIWYPKMGD TAAIFFARSD QAGWDIRAEV DEAILYTQKQ YPHIDINYAV
     LTPVNTHDLV DMNLIAQLFA EDDAAAAAAA NQPNQPNQGQ