ID   VTF3L_VACCT             Reviewed;         382 AA.
AC   Q77TH8;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 36.
DE   RecName: Full=Intermediate transcription factor 3 large subunit;
DE   AltName: Full=VITF-3 45 kDa subunit;
GN   Name=VITF3L; ORFNames=TA24R;
OS   Vaccinia virus (strain Tian Tan) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10253;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Jin Q., Hou Y.D., Cheng N.H., Yao E.M., Cheng S.X., Yang X.K., Jing D.Y.,
RA   Yu W.H., Yuan J.S., Ma X.J.;
RT   "Complete genomic sequence of vaccinia virus (Tian Tan strain).";
RL   Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts with RNA polymerase to initiate transcription from
CC       intermediate gene promoters. {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of a 45 kDa and a 32 kDa subunit. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the poxviruses A23 family. {ECO:0000305}.
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DR   EMBL; AF095689; AAF34019.1; -; Genomic_DNA.
DR   Proteomes; UP000163220; Genome.
DR   InterPro; IPR008789; Poxvirus_intermed-TF.
DR   Pfam; PF05718; Pox_int_trans; 1.
PE   3: Inferred from homology;
KW   Activator; Transcription; Transcription regulation.
FT   CHAIN           1..382
FT                   /note="Intermediate transcription factor 3 large subunit"
FT                   /id="PRO_0000099182"
SQ   SEQUENCE   382 AA;  44637 MW;  126FC844BB7F4BBC CRC64;
     MDNLFTFLHE IEDRYARTIF NFHLISCDEI GDIYGLMKER ISSEDMFDNI VYNKDIHHAI
     KKLVYCDIQL TKHIINQNTY PVFNDSSQVK CCHYFDINSD NSNISSRTVE IFEREKSSLV
     SYIKTTNKKR KVNYGEIKKT VHGGTNANYF SGKKSDEYLS TTVRSNINQP WIKTISKRMR
     VDIINHSIVT RGKSSILQTI EIIFTNRTCV KIFKDSTMHI ILSKDKDEKG CIHMIDKLFY
     VYYNLFLLFE DIIQNEYFKE VANVVNHVLT ATALDEKLFL IKKMAEHDVY GVSNFKIGMF
     NLTFIKSLDH TVFPSLLDED SKIKFFKGKK LNIVALRSLE DCINYVTKSE NMIEMMKERS
     TILNSIDIET ESVDRLKELL LK