ID   VTF3S_VACCA             Reviewed;         288 AA.
AC   P68719; O57221; Q80HV9;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   23-FEB-2022, entry version 44.
DE   RecName: Full=Intermediate transcription factor 3 small subunit;
DE   AltName: Full=VITF-3 32 kDa subunit;
DE   AltName: Full=VITF-3 small subunit;
GN   Name=VITF3S; OrderedLocusNames=MVA119R, ACAM3000_MVA_119; ORFNames=A8R;
OS   Vaccinia virus (strain Ankara) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=126794;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9601507; DOI=10.1006/viro.1998.9123;
RA   Antoine G., Scheiflinger F., Dorner F., Falkner F.G.;
RT   "The complete genomic sequence of the modified vaccinia Ankara strain:
RT   comparison with other orthopoxviruses.";
RL   Virology 244:365-396(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate Acambis 3000;
RA   Esposito J.J., Frace M., Sammons S.A., Olsen-Rasmussen M.S., Osborne J.,
RA   Khristova M., Wohlhueter R.M.;
RL   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts with RNA polymerase to initiate transcription from
CC       intermediate gene promoters. {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of a 45 kDa (A23R) and a 32 kDa (A8R) subunit to
CC       form the virus intermediate transcription factor (VITF)-3.
CC       {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae A8 family. {ECO:0000305}.
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DR   EMBL; U94848; AAB96520.1; -; Genomic_DNA.
DR   EMBL; AY603355; AAT10517.1; -; Genomic_DNA.
DR   PIR; T37395; T37395.
DR   RefSeq; YP_233009.1; NC_006998.1.
DR   DNASU; 3707525; -.
DR   GeneID; 3707525; -.
DR   KEGG; vg:3707525; -.
DR   Proteomes; UP000159908; Genome.
DR   Proteomes; UP000172909; Genome.
DR   InterPro; IPR006834; Pox_A8.
DR   Pfam; PF04745; Pox_A8; 1.
PE   2: Evidence at transcript level;
KW   Activator; Early protein; Transcription; Transcription regulation.
FT   CHAIN           1..288
FT                   /note="Intermediate transcription factor 3 small subunit"
FT                   /id="PRO_0000099190"
SQ   SEQUENCE   288 AA;  33575 MW;  49E0C362F8372235 CRC64;
     MFEPVPDLNL EASVELGEVN IDQTTPMIKE NSGFISRSRR LFAHRSKDDE RKLALRFFLQ
     RLYFLDHREI HYLFRCVDAV KDVTITKKNN IIVAPYIALL TIASKGCKLT ETMIEAFFPE
     LYNEHSKKFK FNSQVSIIQE KLGYQFGNYH VYDFEPYYST VALAIRDEHS SGIFNIRQES
     YLVSSLSEIT YRFYLINLKS DLVQWSASTG AVINQMVNTV LITVYEKLQL VIENDSQFTC
     SLAVESKLPI KLLKDRNELF TKFINELKKT SSFKISKRDK DTLLKYFT