ID   VTF3S_VACCC             Reviewed;         288 AA.
AC   P20986;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   23-FEB-2022, entry version 66.
DE   RecName: Full=Intermediate transcription factor 3 small subunit;
DE   AltName: Full=VITF-3 32 kDa subunit;
DE   AltName: Full=VITF-3 small subunit;
GN   Name=VITF3S; ORFNames=A8R;
OS   Vaccinia virus (strain Copenhagen) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10249;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=2219722; DOI=10.1016/0042-6822(90)90294-2;
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "The complete DNA sequence of vaccinia virus.";
RL   Virology 179:247-266(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Goebel S.J., Johnson G.P., Perkus M.E., Davis S.W., Winslow J.P.,
RA   Paoletti E.;
RT   "Appendix to 'The complete DNA sequence of vaccinia virus'.";
RL   Virology 179:517-563(1990).
CC   -!- FUNCTION: Acts with RNA polymerase to initiate transcription from
CC       intermediate gene promoters. {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of a 45 kDa (A23R) and a 32 kDa (A8R) subunit to
CC       form the virus intermediate transcription factor (VITF)-3.
CC       {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae A8 family. {ECO:0000305}.
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DR   EMBL; M35027; AAA48127.1; -; Genomic_DNA.
DR   PIR; A42518; A42518.
DR   DIP; DIP-2184N; -.
DR   IntAct; P20986; 1.
DR   MINT; P20986; -.
DR   Proteomes; UP000008269; Genome.
DR   InterPro; IPR006834; Pox_A8.
DR   Pfam; PF04745; Pox_A8; 1.
PE   2: Evidence at transcript level;
KW   Activator; Early protein; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..288
FT                   /note="Intermediate transcription factor 3 small subunit"
FT                   /id="PRO_0000099191"
SQ   SEQUENCE   288 AA;  33576 MW;  49EDAED42E372235 CRC64;
     MFEPVPDLNL EASVELGEVN IDQTTPMIKE NSGFISRSRR LFAHRSKDDE RKLALRFFLQ
     RLYFLDHREI HYLFRCVDAV KDVTITKKNN IIVAPYIALL TIASKGCKLT ETMIEAFFPE
     LYNEHSKKFK FNSQVSIIQE KLGYQFGNYH VYDFEPYYST VALAIRDEHS SGIFNIRQES
     YLVSSLSEIT YRFYLINLKS DLVQWSASTG AVINQMVNTV LITVYEKLQL VIENDSQFTC
     SLAVESELPI KLLKDRNELF TKFINELKKT SSFKISKRDK DTLLKYFT