ID   VTM2L_MOUSE             Reviewed;         220 AA.
AC   Q6PDS0;
DT   12-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=V-set and transmembrane domain-containing protein 2-like protein;
DE   Flags: Precursor;
GN   Name=Vstm2l; Synonyms=Gm691;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; BC058538; AAH58538.1; -; mRNA.
DR   RefSeq; NP_941029.2; NM_198627.2.
DR   AlphaFoldDB; Q6PDS0; -.
DR   SMR; Q6PDS0; -.
DR   iPTMnet; Q6PDS0; -.
DR   PhosphoSitePlus; Q6PDS0; -.
DR   PaxDb; Q6PDS0; -.
DR   PRIDE; Q6PDS0; -.
DR   ProteomicsDB; 297593; -.
DR   DNASU; 277432; -.
DR   GeneID; 277432; -.
DR   KEGG; mmu:277432; -.
DR   CTD; 128434; -.
DR   MGI; MGI:2685537; Vstm2l.
DR   eggNOG; ENOG502RY0S; Eukaryota.
DR   InParanoid; Q6PDS0; -.
DR   OrthoDB; 1216208at2759; -.
DR   PhylomeDB; Q6PDS0; -.
DR   BioGRID-ORCS; 277432; 0 hits in 74 CRISPR screens.
DR   ChiTaRS; Vstm2l; mouse.
DR   PRO; PR:Q6PDS0; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; Q6PDS0; protein.
DR   GO; GO:0030424; C:axon; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0098632; F:cell-cell adhesion mediator activity; IBA:GO_Central.
DR   GO; GO:0007411; P:axon guidance; IBA:GO_Central.
DR   GO; GO:0070593; P:dendrite self-avoidance; IBA:GO_Central.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IBA:GO_Central.
DR   GO; GO:0043524; P:negative regulation of neuron apoptotic process; IDA:UniProtKB.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013106; Ig_V-set.
DR   InterPro; IPR027115; VSTM2L.
DR   PANTHER; PTHR12207:SF29; PTHR12207:SF29; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00409; IG; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Immunoglobulin domain; Reference proteome; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..220
FT                   /note="V-set and transmembrane domain-containing protein 2-
FT                   like protein"
FT                   /id="PRO_0000015165"
FT   DOMAIN          41..158
FT                   /note="Ig-like"
FT   REGION          165..220
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..180
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        62..142
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
SQ   SEQUENCE   220 AA;  23723 MW;  901DDDED57AEAA3F CRC64;
     MGAPLAAALG ALHYLALFLQ LGGATRPAGH APWDNHVSGH ALFTETPHDM TARTGEDVEM
     ACSFRGSGSP SYSLEIQWWY LRSHRDWTDK QTWASNQLKA SQQEDSGKDA TKISVVKVVG
     SNISHKLRLS RVKPTDEGTY ECRVIDFSDG GRGVPRVLCL LIPLPAPPRA PRPRGQPPGE
     EPGRGPTLLF LIILPGTGSG TPREAEPHQP HAGGCPARQS