ID   VTS1_DEBHA              Reviewed;         577 AA.
AC   Q6BSL1; B5RTF5;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=RNA-binding protein VTS1;
GN   Name=VTS1; OrderedLocusNames=DEHA2D08030g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: RNA-binding protein involved in post-transcriptional
CC       regulation through transcript degradation.
CC       {ECO:0000250|UniProtKB:Q08831}.
CC   -!- SUBUNIT: Monomer. Binds to RNA. {ECO:0000250|UniProtKB:Q08831}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:Q08831}. Cytoplasm, P-body
CC       {ECO:0000250|UniProtKB:J9VVN9}.
CC   -!- SIMILARITY: Belongs to the VTS1 family. {ECO:0000305}.
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DR   EMBL; CR382136; CAR65640.1; -; Genomic_DNA.
DR   RefSeq; XP_002770284.1; XM_002770238.1.
DR   AlphaFoldDB; Q6BSL1; -.
DR   SMR; Q6BSL1; -.
DR   STRING; 4959.XP_002770284.1; -.
DR   EnsemblFungi; CAR65640; CAR65640; DEHA2D08030g.
DR   GeneID; 8998495; -.
DR   KEGG; dha:DEHA2D08030g; -.
DR   VEuPathDB; FungiDB:DEHA2D08030g; -.
DR   eggNOG; KOG3791; Eukaryota.
DR   HOGENOM; CLU_443421_0_0_1; -.
DR   InParanoid; Q6BSL1; -.
DR   OMA; NLQHEFE; -.
DR   OrthoDB; 1068685at2759; -.
DR   Proteomes; UP000000599; Chromosome D.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR   GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0043488; P:regulation of mRNA stability; IEA:InterPro.
DR   CDD; cd09556; SAM_VTS1_fungal; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR037635; VTS1_SAM.
DR   SMART; SM00454; SAM; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleotide-binding; Protein transport; Reference proteome;
KW   RNA-binding; Transport.
FT   CHAIN           1..577
FT                   /note="RNA-binding protein VTS1"
FT                   /id="PRO_0000081450"
FT   DOMAIN          515..576
FT                   /note="SAM"
FT   REGION          1..41
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          286..355
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          415..510
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..41
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        430..445
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        452..510
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   577 AA;  63544 MW;  09379A8A57A6D3EB CRC64;
     MDRPGFSSPP FNDKKIVLSP PPIESKQYSF LQQHNANSGP PVGFQERQQS VGYNLQQEFE
     TLTADLDLDL RNNKDMQQNV DAPLPTTQSG NVGRGMMPST SQYGFGELGT GGSLQNALLT
     DAALSPNLPT ASSHSALGSL LNNNGNGSFL PPLASIPNRP QSVNDFSNFF NRQQQQQQTI
     DRQQQQQATN FYSDLIVFCN WIETLNPRDN ITMIDYLCNN LPLDILLTFK SKLDSHLTHY
     HNQSATSQPL HQQQNQPVSF GVLSPYQQQQ NDILAEMENL NLDNSLSSDA GASLNQKSAP
     ALQQPKPKLN SVRNHGSHLY AEQQTQRPRS ADPNIHKYSP NYNLPQQQFE RTKSPTSHLY
     EKTNFLQLAA ANSNPPSVSQ QKGANNSDDS VDLSAHAALK LGALATINSR VALDSNRKSH
     VHSAHGHQQP HSHYFPQQGA SQHGPFSPAS AYEESINRSA NSSSVPILVQ HNKSPPGLTR
     SKKSTEGLGQ GANASSGSPQ TTSTTSMPAD ISNPDLLNNI PAWLKLLRLH KYTDCLKDIY
     WKDLIEYDDL SLEKRGVKAL GARRKLLKAF DAVKESS