VTS1_USTMA
ID VTS1_USTMA Reviewed; 728 AA.
AC Q4P965; A0A0D1C519;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=RNA-binding protein VTS1;
GN Name=VTS1; ORFNames=UMAG_03348;
OS Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX NCBI_TaxID=237631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=521 / FGSC 9021;
RX PubMed=17080091; DOI=10.1038/nature05248;
RA Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA Birren B.W.;
RT "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT maydis.";
RL Nature 444:97-101(2006).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=521 / FGSC 9021;
RA Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: RNA-binding protein involved in post-transcriptional
CC regulation through transcript degradation.
CC {ECO:0000250|UniProtKB:Q08831}.
CC -!- SUBUNIT: Monomer. Binds to RNA. {ECO:0000250|UniProtKB:Q08831}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000250|UniProtKB:Q08831}. Cytoplasm, P-body
CC {ECO:0000250|UniProtKB:J9VVN9}.
CC -!- SIMILARITY: Belongs to the VTS1 family. {ECO:0000305}.
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DR EMBL; CM003147; KIS68782.1; -; Genomic_DNA.
DR RefSeq; XP_011389738.1; XM_011391436.1.
DR AlphaFoldDB; Q4P965; -.
DR SMR; Q4P965; -.
DR STRING; 5270.UM03348P0; -.
DR EnsemblFungi; KIS68782; KIS68782; UMAG_03348.
DR GeneID; 23563826; -.
DR KEGG; uma:UMAG_03348; -.
DR VEuPathDB; FungiDB:UMAG_03348; -.
DR eggNOG; KOG3791; Eukaryota.
DR HOGENOM; CLU_017632_1_0_1; -.
DR InParanoid; Q4P965; -.
DR OMA; ANFDKDP; -.
DR OrthoDB; 1052795at2759; -.
DR Proteomes; UP000000561; Chromosome 8.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0000932; C:P-body; IBA:GO_Central.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0030371; F:translation repressor activity; IBA:GO_Central.
DR GO; GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IBA:GO_Central.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd09556; SAM_VTS1_fungal; 1.
DR Gene3D; 1.10.150.50; -; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR037635; VTS1_SAM.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SSF47769; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleotide-binding; Protein transport; Reference proteome;
KW RNA-binding; Transport.
FT CHAIN 1..728
FT /note="RNA-binding protein VTS1"
FT /id="PRO_0000081456"
FT DOMAIN 611..672
FT /note="SAM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00184"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 57..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 210..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 261..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 456..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..32
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..323
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..710
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 728 AA; 76572 MW; EEF820E34E49E98D CRC64;
MSDFGLLRSP LTPSNASINR ASSPSGHRPI TMNPHSRYSL GKGASTEHMM RLAQHGNAGH
DGALRSPSIG GNAPMPGSAG PRNLRPSSEM LPNMNHHGTP ESEAIDRWFE DLQHYEATLE
EMAAASLDQN FKEELSAIEQ WFRVLSEAER TAALYSLLQE STQVQIRFFI TVLQQMARSD
PVSALLSPSH HNSTMADQME AKLASLGLKS PSALKSPASP GNRGYRQSSD AAGFLSPNVA
AMYSPGNTDA ASTLAAQRAK LKANRTSAPG TLIGESRNYS GGQLDQVQER GGSPNLQQQR
TLSGDHSRPK STDFSNNNVG RSPRASGPLD DQLSPISATG NWSSMVNTPL VPMFTDNDKA
GTGEANVNLD TAAAQLASLQ QQQQVGGNGR VMVDPDVPRF RRKSNQNIGG GGSSYGQGPN
LYDHTSPGVS PNIGVPSGWG QSDNFGRGGL NTGLSAFGGN NDSNSNQFNI PPMSPNALAG
LQSPSGGLAN PLNMQVMNMM AAMGGLNLNN MNGAQLLAMQ QQLLQNQQAL SMLAQQQQLQ
QQQPHGRNLG NFGGGGLSPG LAGQAGRKSP RSGTSPSVRA AALPGAAGGA GSGGAGASNA
AGGEEEVADL STLEDVPAWL RQLRLHKYTP NFETSHWKEM VMMGDKQLED KGVAALGARR
KMLKTFELVR KKYGIRMDGE DRPGSGVPDG NNDKAADVDD AGDSNEAQEV DRELGGAATA
ASAPVAKD
