ID   VU94_HHV6U              Reviewed;         490 AA.
AC   Q00683;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   29-SEP-2021, entry version 74.
DE   RecName: Full=Protein U94;
GN   Name=U94; Synonyms=HCLF2, REP;
OS   Human herpesvirus 6A (strain Uganda-1102) (HHV-6 variant A) (Human B
OS   lymphotropic virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=10370;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1851252; DOI=10.1038/351078a0;
RA   Thomson B.J., Efstathiou S., Honess R.W.;
RT   "Acquisition of the human adeno-associated virus type-2 rep gene by human
RT   herpesvirus type-6.";
RL   Nature 351:78-80(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1321205; DOI=10.1099/0022-1317-73-7-1649;
RA   Thomson B.J., Honess R.W.;
RT   "The right end of the unique region of the genome of human herpesvirus 6
RT   U1102 contains a candidate immediate early gene enhancer and a homologue of
RT   the human cytomegalovirus US22 gene family.";
RL   J. Gen. Virol. 73:1649-1660(1992).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=7747482; DOI=10.1006/viro.1995.1228;
RA   Gompels U.A., Nicholas J., Lawrence G.L., Jones M., Thomson B.J.,
RA   Martin M.E.D., Efstathiou S., Craxton M.A., Macaulay H.A.;
RT   "The DNA sequence of human herpesvirus-6: structure, coding content, and
RT   genome evolution.";
RL   Virology 209:29-51(1995).
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DR   EMBL; X59532; CAA42112.1; -; Genomic_DNA.
DR   EMBL; D11134; BAA01906.1; -; Genomic_DNA.
DR   EMBL; X83413; CAA58343.1; -; Genomic_DNA.
DR   PIR; JQ1630; JQ1630.
DR   RefSeq; NP_042987.1; NC_001664.2.
DR   SMR; Q00683; -.
DR   PRIDE; Q00683; -.
DR   DNASU; 1487970; -.
DR   GeneID; 1487970; -.
DR   KEGG; vg:1487970; -.
DR   Proteomes; UP000009295; Genome.
DR   GO; GO:0019079; P:viral genome replication; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001257; Parvovirus_NS1_helicase.
DR   InterPro; IPR014835; Rep_N.
DR   Pfam; PF01057; Parvo_NS1; 1.
DR   Pfam; PF08724; Rep_N; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..490
FT                   /note="Protein U94"
FT                   /id="PRO_0000116299"
SQ   SEQUENCE   490 AA;  55848 MW;  221CE58165187C1F CRC64;
     MFSIINPSDD FWTKDKYIML TIKGPMEWEA EIPGISTDFF CKFSNVSVPH FRDMHSPGAP
     DIKWITACTK MIDVILNYWN NKTAVPTPAK WYAQAENKAG RPSLILLIAL DGIPSATIGK
     HTTEIRGVLI KDFFDGNAPK IDDWCTYAKT KKNGGGTQVF SLSYIPFALL QIIRPQFQWA
     WTNINELGDV CDEIHRKHII SHFNKKPNVK LMLFPKDGIN GISLKSKFLG TIEWLSDLGI
     VTEDAWIRRD IRSYMQLLTL THGDVLIHRA LSIAKKRIRA TRKAIDFIAH IDTDFQIYEN
     PVYQLFCLQS FDPILAGTIL YQWLSHRGGK KNTVSFIGPP GCGKSMLTGA ILENIPLHGI
     LHGSLNTKNL RAYGQVLVLW WKDISINFDN FNIIKSLLGG QKIIFPINEN DHVQIGPCPI
     IATSCVDIRS MVHSNLHKIN LSQRVYNFTF DKVIPRNFPV IQKDDINQFL FWARNRSINC
     FIDYTVPKIL