ID   VU94_HHV6Z              Reviewed;         490 AA.
AC   Q9WSZ6; Q77PU5;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Protein U94;
GN   Name=U94;
OS   Human herpesvirus 6B (strain Z29) (HHV-6 variant B) (Human B lymphotropic
OS   virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=36351;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HST;
RX   PubMed=10482554; DOI=10.1128/jvi.73.10.8053-8063.1999;
RA   Isegawa Y., Mukai T., Nakano K., Kagawa M., Chen J., Mori Y., Sunagawa T.,
RA   Kawanishi K., Sashihara J., Hata A., Zou P., Kosuge H., Yamanishi K.;
RT   "Comparison of the complete DNA sequences of human herpesvirus 6 variants A
RT   and B.";
RL   J. Virol. 73:8053-8063(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10482553; DOI=10.1128/jvi.73.10.8040-8052.1999;
RA   Dominguez G., Dambaugh T.R., Stamey F.R., Dewhurst S., Inoue N.,
RA   Pellett P.E.;
RT   "Human herpesvirus 6B genome sequence: coding content and comparison with
RT   human herpesvirus 6A.";
RL   J. Virol. 73:8040-8052(1999).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB021506; BAA78311.1; -; Genomic_DNA.
DR   EMBL; AF157706; AAD49678.1; -; Genomic_DNA.
DR   PIR; T44050; T44050.
DR   RefSeq; NP_050269.1; NC_000898.1.
DR   SMR; Q9WSZ6; -.
DR   PRIDE; Q9WSZ6; -.
DR   DNASU; 1497090; -.
DR   GeneID; 1497090; -.
DR   KEGG; vg:1497090; -.
DR   Proteomes; UP000006930; Genome.
DR   Proteomes; UP000142685; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0019079; P:viral genome replication; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001257; Parvovirus_NS1_helicase.
DR   InterPro; IPR014835; Rep_N.
DR   Pfam; PF01057; Parvo_NS1; 1.
DR   Pfam; PF08724; Rep_N; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   ATP-binding; DNA replication; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..490
FT                   /note="Protein U94"
FT                   /id="PRO_0000408459"
FT   DOMAIN          312..463
FT                   /note="SF3 helicase"
FT   BINDING         338..345
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   490 AA;  56031 MW;  65587DD9B24A9CDD CRC64;
     MFSIINPSDD FWTKDKYIML TIKGPVEWEA EIPGISTDFF CKFSNVPVPH FRDMHSPGAP
     DIKWITACTK MIDVILNYWN NKTAVPTPAK WYAQAENKAG RPSLTLLIAL DGIPTATIGK
     HTTEIRGVLI KDFFDGNAPK IDDWCTYAKT KKNGGGTQVF SLSYIPFALL QIIRPQFQWA
     WTNINELGDV CDEIHRKHII SHFNKKPNVK LMLFPKDGTN RISLKSKFLG TIEWLSDLGI
     VTEDAWIRRD VRSYMQLLTL THGDVLIHRA LSISKKRIRA TRKAIDFIAH IDTDFEIYEN
     PVYQLFCLQS FDPILAGTIL YQWLSHRRGK KNTVSFIGPP GCGKSMLTGA ILENIPLHGI
     LHGSLNTKNL RAYGQVLVLW WKDISINFEN FNIIKSLLGG QKIIFPINEN DHVQIGPCPI
     IATSCVDIRS MVHSNIHKIN LSQRVYNFTF DKVIPRNFPV IQKDDINQFL FWARNRSINC
     FIDYTVPKIL