ID   VUP3_ARATH              Reviewed;         130 AA.
AC   Q56YT7; B3H6S0;
DT   25-OCT-2017, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Vascular-related unknown protein 3 {ECO:0000303|PubMed:24567189};
GN   Name=VUP3 {ECO:0000303|PubMed:24567189};
GN   OrderedLocusNames=At3g20557 {ECO:0000312|Araport:AT3G20557};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA   Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT   features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT   clones.";
RL   DNA Res. 7:217-221(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   FUNCTION.
RX   PubMed=24567189; DOI=10.1104/pp.114.236406;
RA   Grienenberger E., Douglas C.J.;
RT   "Arabidopsis VASCULAR-RELATED UNKNOWN PROTEIN1 regulates xylem development
RT   and growth by a conserved mechanism that modulates hormone signaling.";
RL   Plant Physiol. 164:1991-2010(2014).
CC   -!- FUNCTION: Involved in the regulation of plant growth.
CC       {ECO:0000269|PubMed:24567189}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q56YT7-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q56YT7-2; Sequence=VSP_059136, VSP_059137;
CC   -!- MISCELLANEOUS: Plants overexpressing VUP3 exhibit severe dwarfism.
CC       {ECO:0000269|PubMed:24567189}.
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DR   EMBL; AP000410; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002686; AEE76396.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE76397.1; -; Genomic_DNA.
DR   EMBL; DQ487564; ABF59233.1; -; mRNA.
DR   EMBL; AK221234; BAD93837.1; -; mRNA.
DR   RefSeq; NP_001030732.1; NM_001035655.3. [Q56YT7-1]
DR   RefSeq; NP_001118667.1; NM_001125195.1. [Q56YT7-2]
DR   AlphaFoldDB; Q56YT7; -.
DR   STRING; 3702.AT3G20557.1; -.
DR   PaxDb; Q56YT7; -.
DR   PRIDE; Q56YT7; -.
DR   EnsemblPlants; AT3G20557.1; AT3G20557.1; AT3G20557. [Q56YT7-1]
DR   EnsemblPlants; AT3G20557.2; AT3G20557.2; AT3G20557. [Q56YT7-2]
DR   GeneID; 3768762; -.
DR   Gramene; AT3G20557.1; AT3G20557.1; AT3G20557. [Q56YT7-1]
DR   Gramene; AT3G20557.2; AT3G20557.2; AT3G20557. [Q56YT7-2]
DR   KEGG; ath:AT3G20557; -.
DR   Araport; AT3G20557; -.
DR   TAIR; locus:1009023249; AT3G20557.
DR   eggNOG; KOG2667; Eukaryota.
DR   HOGENOM; CLU_160247_0_0_1; -.
DR   InParanoid; Q56YT7; -.
DR   OMA; GIMIEEY; -.
DR   OrthoDB; 1490373at2759; -.
DR   PhylomeDB; Q56YT7; -.
DR   PRO; PR:Q56YT7; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q56YT7; baseline and differential.
DR   GO; GO:0009825; P:multidimensional cell growth; IMP:UniProtKB.
DR   GO; GO:0010089; P:xylem development; IEA:InterPro.
DR   InterPro; IPR039280; VUP.
DR   PANTHER; PTHR33974; PTHR33974; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..130
FT                   /note="Vascular-related unknown protein 3"
FT                   /id="PRO_0000441923"
FT   REGION          45..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..77
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         95..107
FT                   /note="EKILNKNGIKIEE -> VRNFMFSNISFHK (in isoform 2)"
FT                   /id="VSP_059136"
FT   VAR_SEQ         108..130
FT                   /note="Missing (in isoform 2)"
FT                   /id="VSP_059137"
SQ   SEQUENCE   130 AA;  14575 MW;  E86A62C0DD439CC1 CRC64;
     MENSALSNCV RRTNFSNQQR TMQEGLEESS WTMYFETEDG LGHYDDSSMM SDAASPMGCV
     EEDTASSPSN RTEGYSGMED NTIEEKTMNN GKIEEKILNK NGIKIEEYCA ELKKRGLCLV
     PLSMLSNYIG