ID   VUP4_ARATH              Reviewed;         165 AA.
AC   Q5BPG5; Q9FFU9;
DT   25-OCT-2017, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Vascular-related unknown protein 4 {ECO:0000303|PubMed:24567189};
GN   Name=VUP4 {ECO:0000303|PubMed:24567189};
GN   OrderedLocusNames=At5g54790 {ECO:0000312|Araport:AT5G54790};
GN   ORFNames=MBG8.5 {ECO:0000312|EMBL:BAB08758.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9330910; DOI=10.1093/dnares/4.3.215;
RA   Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M.,
RA   Miyajima N., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence
RT   features of the 1.6 Mb regions covered by twenty physically assigned P1
RT   clones.";
RL   DNA Res. 4:215-230(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA   Redman J.C., Wu H.C., Utterback T., Town C.D.;
RT   "Reconstruction of cDNA sequences for hypothetical genes in Arabidopsis
RT   thaliana from 5' and 3' RACE products.";
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   FUNCTION.
RX   PubMed=24567189; DOI=10.1104/pp.114.236406;
RA   Grienenberger E., Douglas C.J.;
RT   "Arabidopsis VASCULAR-RELATED UNKNOWN PROTEIN1 regulates xylem development
RT   and growth by a conserved mechanism that modulates hormone signaling.";
RL   Plant Physiol. 164:1991-2010(2014).
CC   -!- FUNCTION: Involved in the regulation of plant growth.
CC       {ECO:0000269|PubMed:24567189}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=1;
CC         Comment=A number of isoforms are produced. According to EST
CC         sequences. {ECO:0000305};
CC       Name=1;
CC         IsoId=Q5BPG5-1; Sequence=Displayed;
CC   -!- MISCELLANEOUS: Plants overexpressing VUP4 exhibit severe dwarfism.
CC       {ECO:0000269|PubMed:24567189}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB08758.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AB005232; BAB08758.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002688; AED96541.1; -; Genomic_DNA.
DR   EMBL; AY924863; AAX23938.1; -; mRNA.
DR   EMBL; DQ132755; AAZ52785.1; -; mRNA.
DR   RefSeq; NP_200290.2; NM_124860.2. [Q5BPG5-1]
DR   AlphaFoldDB; Q5BPG5; -.
DR   PaxDb; Q5BPG5; -.
DR   PRIDE; Q5BPG5; -.
DR   EnsemblPlants; AT5G54790.1; AT5G54790.1; AT5G54790. [Q5BPG5-1]
DR   GeneID; 835569; -.
DR   Gramene; AT5G54790.1; AT5G54790.1; AT5G54790. [Q5BPG5-1]
DR   KEGG; ath:AT5G54790; -.
DR   Araport; AT5G54790; -.
DR   TAIR; locus:2160160; AT5G54790.
DR   eggNOG; ENOG502SA9A; Eukaryota.
DR   HOGENOM; CLU_092975_0_0_1; -.
DR   InParanoid; Q5BPG5; -.
DR   OMA; KHETTTF; -.
DR   OrthoDB; 1614924at2759; -.
DR   PhylomeDB; Q5BPG5; -.
DR   PRO; PR:Q5BPG5; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q5BPG5; baseline and differential.
DR   GO; GO:0009825; P:multidimensional cell growth; IMP:UniProtKB.
DR   GO; GO:0010089; P:xylem development; IEA:InterPro.
DR   InterPro; IPR039280; VUP.
DR   PANTHER; PTHR33974; PTHR33974; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..165
FT                   /note="Vascular-related unknown protein 4"
FT                   /id="PRO_0000441924"
SQ   SEQUENCE   165 AA;  18063 MW;  5D7A8B94DE87D90B CRC64;
     MESSMNNAFI MSKHETAMFT DDQNPEESSW TMYFEDFFEA SSSIVDVGDF SSSSVSDAAS
     FVATKKTLNV SKQEGSNLDI KRTRNREIPF GRHHDLEDTA SSPSGSPNVY SMMNLQDNNT
     RHGGGIVGDD EKRVSAVPNQ GGLPIDLKKK GLCLVPLSMV TNFLG