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VWA7_RAT
ID   VWA7_RAT                Reviewed;         892 AA.
AC   Q6MG64;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=von Willebrand factor A domain-containing protein 7;
DE   AltName: Full=Protein G7c;
DE   Flags: Precursor;
GN   Name=Vwa7; Synonyms=G7c;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway;
RX   PubMed=15060004; DOI=10.1101/gr.1987704;
RA   Hurt P., Walter L., Sudbrak R., Klages S., Mueller I., Shiina T., Inoko H.,
RA   Lehrach H., Guenther E., Reinhardt R., Himmelbauer H.;
RT   "The genomic sequence and comparative analysis of the rat major
RT   histocompatibility complex.";
RL   Genome Res. 14:631-639(2004).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR   EMBL; BX883045; CAE83982.1; -; Genomic_DNA.
DR   RefSeq; NP_997664.1; NM_212499.2.
DR   RefSeq; XP_017457127.1; XM_017601638.1.
DR   AlphaFoldDB; Q6MG64; -.
DR   SMR; Q6MG64; -.
DR   STRING; 10116.ENSRNOP00000001153; -.
DR   GlyGen; Q6MG64; 1 site.
DR   PaxDb; Q6MG64; -.
DR   Ensembl; ENSRNOT00000001153; ENSRNOP00000001153; ENSRNOG00000000860.
DR   GeneID; 309611; -.
DR   KEGG; rno:309611; -.
DR   UCSC; RGD:1303137; rat.
DR   CTD; 80737; -.
DR   RGD; 1303137; Vwa7.
DR   eggNOG; KOG4475; Eukaryota.
DR   GeneTree; ENSGT00390000011517; -.
DR   HOGENOM; CLU_013884_0_0_1; -.
DR   InParanoid; Q6MG64; -.
DR   OMA; MEPIHYV; -.
DR   OrthoDB; 323781at2759; -.
DR   PhylomeDB; Q6MG64; -.
DR   TreeFam; TF329905; -.
DR   PRO; PR:Q6MG64; -.
DR   Proteomes; UP000002494; Chromosome 20.
DR   Bgee; ENSRNOG00000000860; Expressed in heart and 13 other tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.410; -; 1.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   SUPFAM; SSF53300; SSF53300; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..892
FT                   /note="von Willebrand factor A domain-containing protein 7"
FT                   /id="PRO_0000231633"
FT   DOMAIN          313..495
FT                   /note="VWFA"
FT   REGION          231..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        247..272
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        54
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   892 AA;  96045 MW;  AEF5B03F05D6C92F CRC64;
     MLPVEVPLSQ LGPPVLLLQL LLPPTSAFFP NIWSLLAAPG SITHQDLTEE AALNVTLELF
     LEQPPPGRPH LHLEDYRGRT LLADDIFAAY FGSGFSSRRF RAALGEVSRA NAAQDFLPAS
     KSNPDLHFDA ERLVQGRTRL EGALRETLVA ARALEYTLAR QRLGAALHAL QDFYSHSNWV
     ELGERQPHPH LLWPRRELWS LAQVGDPTCS DCEGLSCPGN MMNLTMLTSG YFGTNPPKPP
     GKCSHGGRFD QSSSQPPRGG INKDSTSPSF SPHHRLHLQA AEVALLASIE ALSLLRSRLG
     TRGFSRLLDI TPASSLSFVL DTTGSMGEEI NAAKIQARRI VEQRQGSPME PVSYILVPFH
     DPGFGPVFTT SDPDSFWQKL TEIHALGGGD EPEMCLSALE LALLHTPPLS DIFVFTDASP
     KDAFLTNRVE SLTRERRCRV TFLVTEDPSR AQGRGRREAL SPSRFEPYEA IALASGGEVI
     FTKDQHIRDV AAVVGESMAG LVTLPLEPPI FTPGEPCVFA VDSLLSKVTV RMHGDISGFW
     IKSPAGLSQG PEEGIGPLGH TRRFGQFWTV TMTDPPQTGS WEIQVAAEGT PRVRVQAQTS
     LDFLFHFGIS AEDGPHPGLY PLTQPVAGLQ TQLLVEVTGL VSRQKLGDGQ PQFSHAVLRR
     VSEGTHLGRV SLEPVGPPER GLLAASLPPT LLSVSVPFSL ELVGQDVGGQ CLRRSAPQPC
     SVAPVLLELS GPPDFLTPGS KAPLSLRVAS FSGPQDVDLR SSVNPSFSLT SNLSRARLGL
     NESAWGCLWL EVPDSAAPDT VVTVTVTVTA VGQGASQVPP THAFLQLLVL AQSSKDQLED
     PTHSAAPVLP PTTPALLPST LVTRGRAGRG TTGKTWWGTV GGVLFLLGCT SW
 
 
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