ID   VXIS_BPML5              Reviewed;          56 AA.
AC   Q05246;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   12-AUG-2020, entry version 75.
DE   RecName: Full=Excisionase {ECO:0000303|PubMed:10652095};
DE   AltName: Full=Gene product 36;
DE            Short=Gp36;
GN   Name=XIS; Synonyms=36;
OS   Mycobacterium phage L5 (Mycobacteriophage L5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Fromanvirus.
OX   NCBI_TaxID=31757;
OH   NCBI_TaxID=1763; Mycobacterium.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8459766; DOI=10.1111/j.1365-2958.1993.tb01131.x;
RA   Hatfull G.F., Sarkis G.J.;
RT   "DNA sequence, structure and gene expression of mycobacteriophage L5: a
RT   phage system for mycobacterial genetics.";
RL   Mol. Microbiol. 7:395-405(1993).
RN   [2]
RP   FUNCTION, AND IDENTIFICATION.
RX   PubMed=10652095; DOI=10.1046/j.1365-2958.2000.01695.x;
RA   Lewis J.A., Hatfull G.F.;
RT   "Identification and characterization of mycobacteriophage L5 excisionase.";
RL   Mol. Microbiol. 35:350-360(2000).
CC   -!- FUNCTION: Excisionase and integrase are necessary for the excision of
CC       prophage from the host genome by site-specific recombination at the att
CC       site. {ECO:0000269|PubMed:10652095}.
CC   -!- SIMILARITY: Belongs to the L5likevirus excisionase protein family.
CC       {ECO:0000305}.
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DR   EMBL; Z18946; CAA79412.1; -; Genomic_DNA.
DR   PIR; S30981; S30981.
DR   RefSeq; NP_039700.1; NC_001335.1.
DR   SMR; Q05246; -.
DR   GeneID; 2942990; -.
DR   KEGG; vg:2942990; -.
DR   Proteomes; UP000002123; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0032359; P:provirus excision; IDA:UniProtKB.
DR   InterPro; IPR009061; DNA-bd_dom_put_sf.
DR   InterPro; IPR041657; HTH_17.
DR   InterPro; IPR010093; SinI_DNA-bd.
DR   Pfam; PF12728; HTH_17; 1.
DR   SUPFAM; SSF46955; SSF46955; 1.
DR   TIGRFAMs; TIGR01764; excise; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Reference proteome; Viral genome excision.
FT   CHAIN           1..56
FT                   /note="Excisionase"
FT                   /id="PRO_0000164758"
SQ   SEQUENCE   56 AA;  6338 MW;  F10B9244398A4D8A CRC64;
     MPPRASIQET ADYLGVSTKT VRNYIADGRL KAVRLGPRLI RVERESVEEL MRPIGK