ID   VXIS_BPP22              Reviewed;         116 AA.
AC   P04889; Q7PCH3;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   13-AUG-1987, sequence version 1.
DT   23-FEB-2022, entry version 67.
DE   RecName: Full=Excisionase;
GN   Name=xis;
OS   Salmonella phage P22 (Bacteriophage P22).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Podoviridae; Lederbergvirus.
OX   NCBI_TaxID=10754;
OH   NCBI_TaxID=90371; Salmonella typhimurium.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3491212; DOI=10.1016/0022-2836(86)90491-2;
RA   Leong J.M., Nunes-Dueby S.E., Oser A.B., Lesser C.F., Youderian P.,
RA   Susskind M.M., Landy A.;
RT   "Structural and regulatory divergence among site-specific recombination
RT   genes of lambdoid phage.";
RL   J. Mol. Biol. 189:603-616(1986).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11053393; DOI=10.1128/jb.182.22.6472-6481.2000;
RA   Vander Byl C.S., Kropinski A.M.B.;
RT   "Sequence of the genome of Salmonella bacteriophage P22.";
RL   J. Bacteriol. 182:6472-6481(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12562822; DOI=10.1128/jb.185.4.1475-1477.2003;
RA   Pedulla M.L., Ford M.E., Karthikeyan T., Houtz J.M., Hendrix R.W.,
RA   Hatfull G.F., Poteete A.R., Gilcrease E.B., Winn-Stapley D.A.,
RA   Casjens S.R.;
RT   "Corrected sequence of the bacteriophage P22 genome.";
RL   J. Bacteriol. 185:1475-1477(2003).
RN   [4]
RP   CHARACTERIZATION, AND FUNCTION.
RX   PubMed=18502866; DOI=10.1128/jb.00170-08;
RA   Mattis A.N., Gumport R.I., Gardner J.F.;
RT   "Purification and characterization of bacteriophage P22 Xis protein.";
RL   J. Bacteriol. 190:5781-5796(2008).
CC   -!- FUNCTION: Part of the excision complex necessary for the excision of
CC       prophage from the host genome by site-specific recombination at the att
CC       site. {ECO:0000269|PubMed:18502866}.
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DR   EMBL; X04052; CAA27686.1; -; Genomic_DNA.
DR   EMBL; BK000583; DAA00999.1; -; Genomic_DNA.
DR   EMBL; AF217253; AAF75003.1; -; Genomic_DNA.
DR   PIR; D24253; RSBPXP.
DR   RefSeq; NP_059585.1; NC_002371.2.
DR   SMR; P04889; -.
DR   GeneID; 1262794; -.
DR   KEGG; vg:1262794; -.
DR   Proteomes; UP000001795; Genome.
DR   Proteomes; UP000007960; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0032359; P:provirus excision; IEA:UniProtKB-KW.
DR   InterPro; IPR041657; HTH_17.
DR   Pfam; PF12728; HTH_17; 1.
PE   1: Evidence at protein level;
KW   DNA recombination; DNA-binding; Reference proteome; Viral genome excision.
FT   CHAIN           1..116
FT                   /note="Excisionase"
FT                   /id="PRO_0000077716"
SQ   SEQUENCE   116 AA;  12755 MW;  471D2A05CB7CB900 CRC64;
     MESHSLTLDE ACAFLKISRP TATNWIRTGR LQATRKDPTK PKSPYLTTRQ ACIAALQSPL
     HTVQVSAGDD ITEELKCHYS AEVKPGTPVS HCRTAKDLSS LLGQRTKGRP QSFMTS