ID   W1002_DICDI             Reviewed;         667 AA.
AC   B0G0Z3;
DT   05-DEC-2018, integrated into UniProtKB/Swiss-Prot.
DT   05-DEC-2018, sequence version 2.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=WD40 repeat-containing protein DDB_G0271002 {ECO:0000305};
GN   ORFNames=DDB_G0271002 {ECO:0000312|EMBL:EDR41116.1};
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689 {ECO:0000312|Proteomes:UP000002195};
RN   [1] {ECO:0000312|Proteomes:UP000002195}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4 {ECO:0000312|Proteomes:UP000002195};
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EDR41116.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AAFI02000005; EDR41116.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; XP_001732958.1; XM_001732906.1.
DR   AlphaFoldDB; B0G0Z3; -.
DR   SMR; B0G0Z3; -.
DR   STRING; 44689.DDB0233561; -.
DR   PaxDb; B0G0Z3; -.
DR   EnsemblProtists; EDR41116; EDR41116; DDB_G0271002.
DR   GeneID; 8617409; -.
DR   KEGG; ddi:DDB_G0271002; -.
DR   dictyBase; DDB_G0271002; -.
DR   eggNOG; ENOG502S8QA; Eukaryota.
DR   HOGENOM; CLU_378320_0_0_1; -.
DR   InParanoid; B0G0Z3; -.
DR   PRO; PR:B0G0Z3; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0097361; C:CIA complex; IBA:GO_Central.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM00320; WD40; 2.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..667
FT                   /note="WD40 repeat-containing protein DDB_G0271002"
FT                   /id="PRO_0000445764"
FT   REPEAT          165..204
FT                   /note="WD 1"
FT                   /evidence="ECO:0000255"
FT   REPEAT          210..249
FT                   /note="WD 2"
FT                   /evidence="ECO:0000255"
FT   REGION          278..301
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          316..345
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          389..440
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        278..298
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        323..345
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        398..413
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        414..428
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   667 AA;  76368 MW;  072D3CC529C55855 CRC64;
     MNETNVNNNN QSNEEVEEIN DEFKLYYDGL QESKHMKYYT NSFKSYENKQ HKRVSSTLVP
     LKSEDLQSIR INTIHILAWK LNLMAVSYNS KFIFTAESDV INVRNIDNPN IIIKTFAMDT
     MEMTINQIRL GILDGEEVLV SVDEGGFVRI IFVNDFEREV IRLYNHGVST WGIAICPSKP
     LIAVSSNSHK ITIWNLDDEN PQETKFLLPK HKHNIPSIDF SPCGNYLVSV SIDKNIRIWD
     VNKRQLLRIQ TLAQWCWACR WIDLTTKEDQ LYQYYNNSSN SRDNNNNNSN SNNNGGGGII
     IDKSWRGLTQ HEEQQLVENN QEVEPMPEEE EEEEEEEVNQ VDNDDEIFQE NDDNEENEEN
     TEFLNEANDG VDDDDDLIIQ NGVFTNEDDI IFDGGLPPIN QHQQQQQQNQ EIEEEGQEGQ
     EEQEDGTENE NNQGTIATTT TTTTTIINSI KKLEDAINQQ RIENNRINSK VPLDKNKLPS
     NVVFSTYQNL YLSDVEMDLL LTMNNAIPTS FPIIQTQIDR IAFLEVVPEL SLVIAASQGP
     ARLISLYRIV KQIPLNNNIN NNENNNNENN DNNLNEPETN MFLESVLSPP SGGPGLIVGL
     SVVKNYVKNN PLAFSINLYV MYINGIFINF HIKRSTIRNK PIHQNSTFFD PINKCNIFGL
     DITSFGV