ID   W4936_FUSPC             Reviewed;         406 AA.
AC   K3VDP7;
DT   10-OCT-2018, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2012, sequence version 1.
DT   25-MAY-2022, entry version 22.
DE   RecName: Full=Probable transcription factor FPSE_09188 {ECO:0000303|PubMed:25412204};
DE   AltName: Full=W493 A and B biosynthesis cluster protein FPSE_09188 {ECO:0000303|PubMed:25412204};
GN   ORFNames=FPSE_09188;
OS   Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX   NCBI_TaxID=1028729;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CS3096;
RX   PubMed=23028337; DOI=10.1371/journal.ppat.1002952;
RA   Gardiner D.M., McDonald M.C., Covarelli L., Solomon P.S., Rusu A.G.,
RA   Marshall M., Kazan K., Chakraborty S., McDonald B.A., Manners J.M.;
RT   "Comparative pathogenomics reveals horizontally acquired novel virulence
RT   genes in fungi infecting cereal hosts.";
RL   PLoS Pathog. 8:E1002952-E1002952(2012).
RN   [2]
RP   IDENTIFICATION, AND FUNCTION.
RX   PubMed=25412204; DOI=10.1021/np500436r;
RA   Soerensen J.L., Sondergaard T.E., Covarelli L., Fuertes P.R., Hansen F.T.,
RA   Frandsen R.J., Saei W., Lukassen M.B., Wimmer R., Nielsen K.F.,
RA   Gardiner D.M., Giese H.;
RT   "Identification of the biosynthetic gene clusters for the lipopeptides
RT   fusaristatin A and W493 B in Fusarium graminearum and F.
RT   pseudograminearum.";
RL   J. Nat. Prod. 77:2619-2625(2014).
CC   -!- FUNCTION: The two putative transcription factors FPSE_09188 and
CC       FPSE_09189 could be responsible for orchestrating expression of the
CC       W493 A and B biosynthesis cluster genes (Probable). W493 A and B
CC       consist of six amino acid residues D-allo-thr, L-Ala, D-Ala, L-Gln, D-
CC       Tyr, and L-Val/L-Ile linked to a 3-hydroxy-4-methyltetradecanoic acid
CC       polyketide chain (PubMed:25412204). {ECO:0000269|PubMed:25412204,
CC       ECO:0000305|PubMed:25412204}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305|PubMed:25412204}.
CC   -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
CC   -!- CAUTION: The N-terminal region is not conserved, preventing the
CC       detection of a bZIP domain. {ECO:0000305}.
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DR   EMBL; AFNW01000306; EKJ70678.1; -; Genomic_DNA.
DR   RefSeq; XP_009260580.1; XM_009262305.1.
DR   AlphaFoldDB; K3VDP7; -.
DR   EnsemblFungi; EKJ70678; EKJ70678; FPSE_09188.
DR   GeneID; 20367805; -.
DR   KEGG; fpu:FPSE_09188; -.
DR   eggNOG; ENOG502SNVG; Eukaryota.
DR   HOGENOM; CLU_678001_0_0_1; -.
DR   InParanoid; K3VDP7; -.
DR   Proteomes; UP000007978; Chromosome 1.
DR   Proteomes; UP000007978; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   DNA-binding; Nucleus; Transcription; Transcription regulation.
FT   CHAIN           1..406
FT                   /note="Probable transcription factor FPSE_09188"
FT                   /id="PRO_0000445378"
FT   REGION          1..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..52
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   406 AA;  44931 MW;  E0EE1EB74042CD8D CRC64;
     MELPTYAVSQ SLLASRSVSS PRGDQPVRAA TNGTQGQGQG QDGQNLTGKR KRTNPGYPSR
     ESPKGSSSRC NGLTQYAVPA SFQSPQIVQY SPPNQILRTP PSNDVDDQLS VNSRSEPVYP
     TLGVPGAVRQ TQEQLQLHAA RIPASHFLNN VPNFGYHSTD KDVAMKQNYF SDSTFFPSPA
     ITDTWGELPA PDLSWETTTR PHSPGNRATP TVDKHVSVSA FEAALETGEL ASDRSIQNAY
     NAPSTTGDNH LETLVSIQDG LSQVLKAVEA AGFDSLDSAV IAYYQRSSKG NEWLRQEQRL
     NRMRRLPVLL KELHLAAQGW GQWERRNFQE QIIKSTEDIL FAELQDHLAT RRNSPHASPC
     SIEQRSQARQ HMMEHDADPE AEFYDTSHGT EGIPADEMLH VNLLLY