ID   WA22_MYCBO              Reviewed;         914 AA.
AC   P0A687; A0A1R3XZ80; A0A1R3Y1D5; O06794; X2BID9;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=WAG22 antigen;
GN   Name=wag22; Synonyms=wag22a, wag22b;
GN   OrderedLocusNames=BQ2027_MB1789C/BQ2027_MB1790C;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SIMILARITY: Belongs to the mycobacterial PE family. PGRS subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=SIU00392.1; Type=Frameshift; Evidence={ECO:0000305};
CC       Sequence=SIU00393.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; LT708304; SIU00392.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; LT708304; SIU00393.1; ALT_FRAME; Genomic_DNA.
DR   RefSeq; NP_855441.1; NC_002945.3.
DR   RefSeq; NP_855442.1; NC_002945.3.
DR   AlphaFoldDB; P0A687; -.
DR   EnsemblBacteria; SIU00392; SIU00392; BQ2027_MB1789C.
DR   EnsemblBacteria; SIU00393; SIU00393; BQ2027_MB1790C.
DR   PATRIC; fig|233413.5.peg.1957; -.
DR   Proteomes; UP000001419; Chromosome.
DR   InterPro; IPR000084; PE-PGRS_N.
DR   Pfam; PF00934; PE; 1.
PE   3: Inferred from homology;
KW   Repeat.
FT   CHAIN           1..914
FT                   /note="WAG22 antigen"
FT                   /id="PRO_0000023573"
FT   DOMAIN          1..93
FT                   /note="PE"
FT                   /evidence="ECO:0000255"
FT   REGION          412..431
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          895..914
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   914 AA;  74354 MW;  F6953C3DBE8E6AC8 CRC64;
     MSFVIAVPET IAAAATDLAD LGSTIAGANA AAAANTTSLL AAGADEISAA IAALFGAHGR
     AYQAASAEAA AFHGRFVQAL TTGGGAYAAA EAAAVTPLLN SINAPVLAAT GRPLIGNGAN
     GAPGTGANGG DAGWLIGNGG AGGSGAKGAN GGAGGPGGAA GLFGNGGAGG AGGTATANNG
     IGGAGGAGGS AMLFGAGGAG GAGGAATSLV GGIGGTGGTG GNAGMLAGAA GAGGAGGFSF
     STAGGAGGAG GAGGLFTTGG VGGAGGQGHT GGAGGAGGAG GLFGAGGMGG AGGFGDHGTL
     GTGGAGGDGG GGGLFGAGGD GGAGGSGLTT GGAAGNGGNA GTLSLGAAGG AGGTGGAGGT
     VFGGGKGGAG GAGGNAGMLF GSGGGGGTGG FGFAAGGQGG VGGSAGMLSG SGGSGGAGGS
     GGPAGTAAGG AGGAGGAPGL IGNGGNGGNG GESGGTGGVG GAGGNAVLIG NGGEGGIGAL
     AGKSGFGGFG GLLLGADGYN APESTSPWHN LQQDILSFIN EPTEALTGRP LIGNGDSGTP
     GTGDDGGAGG WLFGNGGNGG AGAAGTNGSA GGAGGAGGIL FGTGGAGGAG GVGTAGAGGA
     GGAGGSAFLI GSGGTGGVGG AATTTGGVGG AGGNAGLLIG AAGLGGCGGG AFTAGVTTGG
     AGGTGGAAGL FANGGAGGAG GTGSTAGGAG GAGGAGGLYA HGGTGGPGGN GGSTGAGGTG
     GAGGPGGLYG AGGSGGAGGH GGMAGGGGGV GGNAGSLTLN ASGGAGGSGG SSLSGKAGAG
     GAGGSAGLFY GSGGAGGNGG YSLNGTGGDG GTGGAGQITG LRSGFGGAGG AGGASDTGAG
     GNGGAGGKAG LYGNGGDGGA GGDGATSGKG GAGGNAVVIG NGGNGGNAGK AGGTAGAGGA
     GGLVLGRDGQ HGLT