ID   WAAE_KLEPN              Reviewed;         258 AA.
AC   Q9XC90;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Lipopolysaccharide core biosynthesis glycosyltransferase WaaE;
DE            EC=2.4.-.-;
GN   Name=waaE;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=C3;
RX   PubMed=11371519; DOI=10.1128/jb.183.12.3564-3573.2001;
RA   Regue M., Climent N., Abitiu N., Coderch N., Merino S., Izquierdo L.,
RA   Altarriba M., Tomas J.M.;
RT   "Genetic characterization of the Klebsiella pneumoniae waa gene cluster,
RT   involved in core lipopolysaccharide biosynthesis.";
RL   J. Bacteriol. 183:3564-3573(2001).
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; LPS core biosynthesis.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. WaaE/KdtX
CC       subfamily. {ECO:0000305}.
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DR   EMBL; AF146532; AAD37772.1; -; Genomic_DNA.
DR   RefSeq; WP_004145264.1; NZ_WYAL01000009.1.
DR   AlphaFoldDB; Q9XC90; -.
DR   SMR; Q9XC90; -.
DR   CAZy; GT2; Glycosyltransferase Family 2.
DR   UniPathway; UPA00958; -.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009244; P:lipopolysaccharide core region biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR001173; Glyco_trans_2-like.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   Pfam; PF00535; Glycos_transf_2; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
PE   3: Inferred from homology;
KW   Glycosyltransferase; Lipopolysaccharide biosynthesis; Transferase.
FT   CHAIN           1..258
FT                   /note="Lipopolysaccharide core biosynthesis
FT                   glycosyltransferase WaaE"
FT                   /id="PRO_0000059230"
SQ   SEQUENCE   258 AA;  29268 MW;  D7458899030678D9 CRC64;
     MSNRLSVVMI AKNAADLLPD CLGSVSWADE IIVLDSGSTD NTVELARRLG AQVYTHTDWR
     GYGIQRQRAQ DYATGDWVLM IDTDERVTPE LRQAILKVLD APQRGAIYSI ARRNYFLGRF
     MRHSGWYPDR VLRLYERARY RYNDNLVHES LDSLGAEVIP LTGDLLHLTC RDFAGFQQKQ
     LAYAAAWALE RHQKGKKTSM AGIFSHTLGA FLKTLLLRGG VLDGKQGWLL AMVNAQYTFT
     KYTELWALSH GYSEKESS