WAG31_MYCBO
ID WAG31_MYCBO Reviewed; 260 AA.
AC P0A5N3; A0A1R3Y0R4; P46816; X2BKA1;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Cell wall synthesis protein Wag31;
DE AltName: Full=Antigen 84;
GN Name=wag31; Synonyms=ag84; OrderedLocusNames=BQ2027_MB2169C;
OS Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=233413;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT "The complete genome sequence of Mycobacterium bovis.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=ATCC BAA-935 / AF2122/97;
RX PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA Robbe-Austerman S., Gordon S.V.;
RT "Updated reference genome sequence and annotation of Mycobacterium bovis
RT AF2122/97.";
RL Genome Announc. 5:E00157-E00157(2017).
CC -!- FUNCTION: Important for maintaining cell shape and cell wall integrity
CC by localizing peptidoglycan synthesis to the cell poles. {ECO:0000250}.
CC -!- SUBUNIT: Forms homooligomers. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Localizes to the
CC cell poles. {ECO:0000250}.
CC -!- PTM: Phosphorylated by PknA. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DivIVA family. {ECO:0000305}.
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DR EMBL; LT708304; SIU00777.1; -; Genomic_DNA.
DR RefSeq; NP_855818.1; NC_002945.3.
DR RefSeq; WP_003411131.1; NC_002945.4.
DR AlphaFoldDB; P0A5N3; -.
DR SMR; P0A5N3; -.
DR EnsemblBacteria; SIU00777; SIU00777; BQ2027_MB2169C.
DR PATRIC; fig|233413.5.peg.2385; -.
DR OMA; VNKRFQP; -.
DR Proteomes; UP000001419; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR InterPro; IPR019933; DivIVA_domain.
DR InterPro; IPR007793; DivIVA_fam.
DR PANTHER; PTHR35794; PTHR35794; 2.
DR Pfam; PF05103; DivIVA; 1.
DR TIGRFAMs; TIGR03544; DivI1A_domain; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cell shape; Coiled coil; Cytoplasm;
KW Phosphoprotein.
FT CHAIN 1..260
FT /note="Cell wall synthesis protein Wag31"
FT /id="PRO_0000064490"
FT REGION 233..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 31..64
FT /evidence="ECO:0000255"
FT COILED 161..196
FT /evidence="ECO:0000255"
FT MOD_RES 73
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 260 AA; 28277 MW; D36113355149CEDC CRC64;
MPLTPADVHN VAFSKPPIGK RGYNEDEVDA FLDLVENELT RLIEENSDLR QRINELDQEL
AAGGGAGVTP QATQAIPAYE PEPGKPAPAA VSAGMNEEQA LKAARVLSLA QDTADRLTNT
AKAESDKMLA DARANAEQIL GEARHTADAT VAEARQRADA MLADAQSRSE AQLRQAQEKA
DALQADAERK HSEIMGTINQ QRAVLEGRLE QLRTFEREYR TRLKTYLESQ LEELGQRGSA
APVDSNADAG GFDQFNRGKN
