ID   CAMKV_XENLA             Reviewed;         377 AA.
AC   Q6GLS4;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=CaM kinase-like vesicle-associated protein;
GN   Name=camkv;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Does not appear to have detectable kinase activity.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250};
CC   -!- SUBUNIT: Interacts with calmodulin, in the presence of calcium.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane; Peripheral membrane
CC       protein. Note=May be associated with vesicular structures.
CC       {ECO:0000250}.
CC   -!- DOMAIN: The protein kinase domain is predicted to be catalytically
CC       inactive.
CC   -!- SIMILARITY: Belongs to the protein kinase superfamily. CAMK Ser/Thr
CC       protein kinase family. {ECO:0000305}.
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DR   EMBL; BC074382; AAH74382.1; -; mRNA.
DR   RefSeq; NP_001086252.1; NM_001092783.1.
DR   AlphaFoldDB; Q6GLS4; -.
DR   SMR; Q6GLS4; -.
DR   GeneID; 444681; -.
DR   KEGG; xla:444681; -.
DR   CTD; 444681; -.
DR   Xenbase; XB-GENE-943907; camkv.L.
DR   OrthoDB; 330091at2759; -.
DR   Proteomes; UP000186698; Chromosome 4L.
DR   Bgee; 444681; Expressed in brain and 3 other tissues.
DR   GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0006468; P:protein phosphorylation; IEA:InterPro.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   Pfam; PF00069; Pkinase; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   2: Evidence at transcript level;
KW   Calmodulin-binding; Cytoplasmic vesicle; Membrane; Reference proteome.
FT   CHAIN           1..377
FT                   /note="CaM kinase-like vesicle-associated protein"
FT                   /id="PRO_0000250099"
FT   DOMAIN          24..287
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT   REGION          324..377
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        334..353
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   377 AA;  42925 MW;  A9647202188923D4 CRC64;
     MPFGCVTLGD KKDYNHPTEV SDRYDLGQLI KTEEFCEVFR AKEKSSGKLY TCKRFLKRDG
     RKVRKAAKNE INILKMVKHH NILQLVDVFE TRKEYFIFME LASGREVFDW ILDQGYYSEK
     DTSNVIRQVL EAVAYLHSLC VVHRNLKLEN LLYFNRMKNS KIVISDFHLA KVETNSLIKE
     PCGTPEYLAP EVVARQRYGR PVDCWAIGVI MYILLSGNPP FYDELEEEDY ESHDKNLFRK
     ILHGDYEFDS PYWDDISPAA KDLVTRLMEV EQDQRVTAAD AISHEWISGN AASDKNIKDG
     VCAQIEKNFA KAKWKKAVRV TTMMKRLRAP EQTDPGTPSP SKDSDKTPSM ATPAPSPANT
     PAEGAPSLPC PSPDTTG