WAP_ARATH
ID WAP_ARATH Reviewed; 825 AA.
AC O64584;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 2.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=WPP domain-associated protein;
GN Name=WAP; OrderedLocusNames=At2g34730; ORFNames=T29F13.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP INTERACTION WITH WPP2.
RX PubMed=16231153; DOI=10.1007/s00425-005-0076-0;
RA Patel S., Brkljacic J., Gindullis F., Rose A., Meier I.;
RT "The plant nuclear envelope protein MAF1 has an additional location at the
RT Golgi and binds to a novel Golgi-associated coiled-coil protein.";
RL Planta 222:1028-1040(2005).
CC -!- SUBUNIT: Interacts with WPP1/MAF1 and WPP2/MAF2.
CC {ECO:0000305|PubMed:16231153}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000250}. Cytoplasm
CC {ECO:0000250}. Note=Accumulate in speckles of the cytoplasm belonging
CC to the Golgi apparatus. {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=O64584-1; Sequence=Displayed;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC16261.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC003096; AAC16261.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC09014.1; -; Genomic_DNA.
DR PIR; T01362; T01362.
DR RefSeq; NP_181020.2; NM_129027.6. [O64584-1]
DR AlphaFoldDB; O64584; -.
DR SMR; O64584; -.
DR STRING; 3702.AT2G34730.2; -.
DR PaxDb; O64584; -.
DR PRIDE; O64584; -.
DR EnsemblPlants; AT2G34730.1; AT2G34730.1; AT2G34730. [O64584-1]
DR GeneID; 818038; -.
DR Gramene; AT2G34730.1; AT2G34730.1; AT2G34730. [O64584-1]
DR KEGG; ath:AT2G34730; -.
DR Araport; AT2G34730; -.
DR TAIR; locus:2061524; AT2G34730.
DR eggNOG; ENOG502QPVR; Eukaryota.
DR HOGENOM; CLU_015336_0_0_1; -.
DR InParanoid; O64584; -.
DR OMA; LIMQEIC; -.
DR OrthoDB; 217033at2759; -.
DR PhylomeDB; O64584; -.
DR PRO; PR:O64584; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O64584; baseline and differential.
DR Genevisible; O64584; AT.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR InterPro; IPR037490; WAP.
DR PANTHER; PTHR33883; PTHR33883; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Coiled coil; Cytoplasm; Golgi apparatus;
KW Reference proteome.
FT CHAIN 1..825
FT /note="WPP domain-associated protein"
FT /id="PRO_0000347188"
FT COILED 124..147
FT /evidence="ECO:0000255"
FT COILED 251..271
FT /evidence="ECO:0000255"
FT COILED 410..521
FT /evidence="ECO:0000255"
FT COILED 563..788
FT /evidence="ECO:0000255"
SQ SEQUENCE 825 AA; 94604 MW; F28E6BD07BF6682C CRC64;
MEEEVVKSEN GSLEFHDDTL SSSLQVNGVL KENENPDVDF LEDLDSYWED INDRLTISRV
VSDSIIRGMV TAIESDAAEK IAQKDLELSK IRETLLLYHV GSEENESSES RLIHDELTQG
SSSSLKKKAR KQLLMLVEEL TNLREYIHIN GSGATVDDSL GLDSSPHETR SKTVDKMLDS
LKSILETVLK RKNDMELPSS WQQEHDFQKE IESAVVTSVL RSLKDEYEQR LLDQKAEFGG
NRSLILGNIK EITGLRQELE AIRKSFLDHE NGDEAGEVGD RKRVEQLHRK MSGSLNSVSS
VWENGKHEES STGLIPEHNE TLRHMSPDEM INHFKIEMNK MKRDHDYKIQ ELTEQCFTFK
RKYLNLTERG SFSFVGKDKE LGALKKKIPF VISKLDKILM EDEKFVSEGK NDAGLKRQLD
SLLLENRQLK DSLSDAAEKM SQLSQAEADH QELIRKLETD VEDSRNEASI YEDVYGCFVT
EFVGQIKCTK QETDLEHSML REAYELLLED LARKEARKSK EDFEDSCVKS VMMEECCSVI
YKEAVKEAHK KIVELNLHVT EKEGTLRSEM VDKERLKEEI HRLGCLVKEK ENLVQTAENN
LATERKKIEV VSQQINDLQS QVERQETEIQ DKIEALSVVS ARELEKVKGY ETKISSLREE
LELARESLKE MKDEKRKTEE KLSETKAEKE TLKKQLVSLD LVVPPQLIKG FDILEGLIAE
KTQKTNSRLK NMQSQLSDLS HQINEVKGKA STYKQRLEKK CCDLKKAEAE VDLLGDEVET
LLDLLEKIYI ALDHYSPILK HYPGIIEILR LVRRELSGES KRPSG