WAXS9_ARATH
ID WAXS9_ARATH Reviewed; 341 AA.
AC Q4PT07; Q9LNK9;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Probable long-chain-alcohol O-fatty-acyltransferase 9;
DE EC=2.3.1.75;
DE AltName: Full=Wax synthase 9;
GN OrderedLocusNames=At1g34500; ORFNames=F12K21.19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the final step in the synthesis of long-chain
CC linear esters (waxes). {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a fatty acyl-CoA + a long chain fatty alcohol = a wax ester +
CC CoA; Xref=Rhea:RHEA:38443, ChEBI:CHEBI:10036, ChEBI:CHEBI:17135,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:77636; EC=2.3.1.75;
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the wax synthase family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79268.1; Type=Erroneous gene model prediction; Note=The predicted gene has been split into 2 genes: At1g34490 and At1g34500.; Evidence={ECO:0000305};
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DR EMBL; AC023279; AAF79268.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE31720.1; -; Genomic_DNA.
DR EMBL; DQ056479; AAY78636.1; -; mRNA.
DR RefSeq; NP_174709.1; NM_103172.1.
DR AlphaFoldDB; Q4PT07; -.
DR PaxDb; Q4PT07; -.
DR PRIDE; Q4PT07; -.
DR EnsemblPlants; AT1G34500.1; AT1G34500.1; AT1G34500.
DR GeneID; 840352; -.
DR Gramene; AT1G34500.1; AT1G34500.1; AT1G34500.
DR KEGG; ath:AT1G34500; -.
DR Araport; AT1G34500; -.
DR TAIR; locus:2009328; AT1G34500.
DR HOGENOM; CLU_045902_0_0_1; -.
DR InParanoid; Q4PT07; -.
DR OMA; QANEPYL; -.
DR OrthoDB; 853289at2759; -.
DR PhylomeDB; Q4PT07; -.
DR BioCyc; ARA:AT1G34500-MON; -.
DR BRENDA; 2.3.1.75; 399.
DR PRO; PR:Q4PT07; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q4PT07; baseline and differential.
DR Genevisible; Q4PT07; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0102966; F:arachidoyl-CoA:1-dodecanol O-acyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0047196; F:long-chain-alcohol O-fatty-acyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR InterPro; IPR044851; Wax_synthase.
DR InterPro; IPR032805; Wax_synthase_dom.
DR InterPro; IPR017088; Wax_synthase_Magnoliopsida.
DR PANTHER; PTHR31595; PTHR31595; 1.
DR Pfam; PF13813; MBOAT_2; 1.
DR PIRSF; PIRSF037006; Wax_synthase; 1.
PE 2: Evidence at transcript level;
KW Acyltransferase; Lipid biosynthesis; Lipid metabolism; Membrane;
KW Reference proteome; Transferase; Transmembrane; Transmembrane helix.
FT CHAIN 1..341
FT /note="Probable long-chain-alcohol O-fatty-acyltransferase
FT 9"
FT /id="PRO_0000380685"
FT TRANSMEM 9..29
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 146..166
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 295..315
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 341 AA; 39349 MW; 5D51C37B5B9AA2F5 CRC64;
MEEELKNFII VWISAIISVS YCYYISANIK TGVLRLFSVL PICGLFFVLP LFFSSVHFSS
STAFYLSEMA SLKLILFAFD QGPLFPVAPN LIQFVCFTCF PIKLQRNPKS QPSQNHFHKR
AFAIKIMIFG VVLHVYNYSH FLPQTVLLSL CFLHLYVELE ILLGPLKVLL SMALGCDLEP
QFNKPYLATS LQDFWGRRWN LMVSSVLRSG IYNPVRCACQ RPMNSGWARF MGYLVTFLVS
GLFHELVYFY ITRETPTWEV TLFFVLNGVC TGTEVAVKRT AFLQRWWPVR SSVSRLLTMG
FVVVTGGLLF FPLFIRSGMM ERRANETLFF LDFVKRKFSI F
