ID   WAXSB_ARATH             Reviewed;         435 AA.
AC   Q9FGN1;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Probable long-chain-alcohol O-fatty-acyltransferase 11;
DE            EC=2.3.1.75;
DE   AltName: Full=Wax synthase 11;
GN   OrderedLocusNames=At5g51420; ORFNames=MFG13.13;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RA   Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL   Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA   Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the final step in the synthesis of long-chain
CC       linear esters (waxes). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a fatty acyl-CoA + a long chain fatty alcohol = a wax ester +
CC         CoA; Xref=Rhea:RHEA:38443, ChEBI:CHEBI:10036, ChEBI:CHEBI:17135,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:77636; EC=2.3.1.75;
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the wax synthase family. {ECO:0000305}.
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DR   EMBL; AB025621; BAB09753.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED96079.1; -; Genomic_DNA.
DR   EMBL; DQ056715; AAY78861.1; -; mRNA.
DR   RefSeq; NP_199955.1; NM_124521.2.
DR   AlphaFoldDB; Q9FGN1; -.
DR   PaxDb; Q9FGN1; -.
DR   PRIDE; Q9FGN1; -.
DR   EnsemblPlants; AT5G51420.1; AT5G51420.1; AT5G51420.
DR   GeneID; 835216; -.
DR   Gramene; AT5G51420.1; AT5G51420.1; AT5G51420.
DR   KEGG; ath:AT5G51420; -.
DR   Araport; AT5G51420; -.
DR   TAIR; locus:2163650; AT5G51420.
DR   HOGENOM; CLU_045902_0_0_1; -.
DR   InParanoid; Q9FGN1; -.
DR   OMA; IGEYAIL; -.
DR   OrthoDB; 606079at2759; -.
DR   PhylomeDB; Q9FGN1; -.
DR   BioCyc; ARA:AT5G51420-MON; -.
DR   BRENDA; 2.3.1.75; 399.
DR   PRO; PR:Q9FGN1; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FGN1; baseline and differential.
DR   Genevisible; Q9FGN1; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0102966; F:arachidoyl-CoA:1-dodecanol O-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0047196; F:long-chain-alcohol O-fatty-acyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR044851; Wax_synthase.
DR   InterPro; IPR032805; Wax_synthase_dom.
DR   PANTHER; PTHR31595; PTHR31595; 1.
DR   Pfam; PF13813; MBOAT_2; 1.
PE   2: Evidence at transcript level;
KW   Acyltransferase; Lipid biosynthesis; Lipid metabolism; Membrane;
KW   Reference proteome; Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..435
FT                   /note="Probable long-chain-alcohol O-fatty-acyltransferase
FT                   11"
FT                   /id="PRO_0000380687"
FT   TRANSMEM        7..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        238..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        263..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        300..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        363..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        406..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   435 AA;  51287 MW;  70C5442385E39D32 CRC64;
     MEEELKNLIK VSVSVIISIS YCYYVPTRIK PGIFRFLSVL PICALFRVLP LFFASVHLSG
     YTALFISWLA NFKLILFSFN QGPLFPLPSN LTRFICFACF PIKLQQNPKR RDYFFQWEYP
     IEVLFSNQFV TKVVILSVVL HMYNHIQHIY PIVLFVLYPL HLYLVLEILL KLFNAFFSIA
     LDCELEPQLN EPYLAYSLRD FWGHWWTLML PTILLPDVYA RMRRITEGKM NSENALYLGV
     FVTFLVSGAL HEFLFFYITR ERPTGEVTLF FVLHGVCIVA YDARLKKKIA RWIGFEFCPC
     LILQVMVMGF VVVTAGWLFF PPLVRTGKIQ RFANEALLFI GFVRNLFNES LFFMRKFFNE
     ALFFTGFVMR KLFNGALFFI GFVKLKLFNE SSLFFIMRKL FNEAMFFIGF VIRKLFNEAM
     FFIGFVKLKL FTFGW