WBBJ_ECOLI
ID WBBJ_ECOLI Reviewed; 196 AA.
AC P37750; P76375;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-1998, sequence version 2.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ;
DE EC=2.3.1.-;
GN Name=wbbJ; Synonyms=yefH; OrderedLocusNames=b2033, JW2018;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=7517390; DOI=10.1128/jb.176.13.4133-4143.1994;
RA Yao Z., Valvano M.A.;
RT "Genetic analysis of the O-specific lipopolysaccharide biosynthesis region
RT (rfb) of Escherichia coli K-12 W3110: identification of genes that confer
RT group 6 specificity to Shigella flexneri serotypes Y and 4a.";
RL J. Bacteriol. 176:4133-4143(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12 / WG1;
RX PubMed=7517391; DOI=10.1128/jb.176.13.4144-4156.1994;
RA Stevenson G., Neal B., Liu D., Hobbs M., Packer N.H., Batley M.,
RA Redmond J.W., Lindquist L., Reeves P.R.;
RT "Structure of the O antigen of Escherichia coli K-12 and the sequence of
RT its rfb gene cluster.";
RL J. Bacteriol. 176:4144-4156(1994).
RN [3]
RP SEQUENCE REVISION TO 168-176 AND 187-189.
RC STRAIN=K12 / WG1;
RA Stevenson G.;
RL Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA Horiuchi T.;
RT "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 40.1-50.0 min region on the linkage map.";
RL DNA Res. 3:379-392(1996).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: Putative O-acetyltransferase that transfers an O-acetyl group
CC to the O antigen.
CC -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC biosynthesis.
CC -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC {ECO:0000305}.
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DR EMBL; U03041; AAC31635.1; -; Genomic_DNA.
DR EMBL; U09876; AAB88406.1; -; Genomic_DNA.
DR EMBL; U00096; AAC75094.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15875.1; -; Genomic_DNA.
DR PIR; H64968; H64968.
DR RefSeq; NP_416537.1; NC_000913.3.
DR RefSeq; WP_000601187.1; NZ_LN832404.1.
DR AlphaFoldDB; P37750; -.
DR SMR; P37750; -.
DR BioGRID; 4261351; 124.
DR DIP; DIP-11115N; -.
DR IntAct; P37750; 7.
DR STRING; 511145.b2033; -.
DR jPOST; P37750; -.
DR PaxDb; P37750; -.
DR PRIDE; P37750; -.
DR EnsemblBacteria; AAC75094; AAC75094; b2033.
DR EnsemblBacteria; BAA15875; BAA15875; BAA15875.
DR GeneID; 946556; -.
DR KEGG; ecj:JW2018; -.
DR KEGG; eco:b2033; -.
DR PATRIC; fig|1411691.4.peg.218; -.
DR EchoBASE; EB1927; -.
DR eggNOG; COG0110; Bacteria.
DR HOGENOM; CLU_051638_7_0_6; -.
DR InParanoid; P37750; -.
DR OMA; NIEQNVH; -.
DR PhylomeDB; P37750; -.
DR BioCyc; EcoCyc:EG11984-MON; -.
DR UniPathway; UPA00030; -.
DR PRO; PR:P37750; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR GO; GO:0008374; F:O-acyltransferase activity; IBA:GO_Central.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR Pfam; PF00132; Hexapep; 1.
DR SUPFAM; SSF51161; SSF51161; 1.
PE 3: Inferred from homology;
KW Acyltransferase; Lipopolysaccharide biosynthesis; Reference proteome;
KW Repeat; Transferase.
FT CHAIN 1..196
FT /note="Putative lipopolysaccharide biosynthesis O-acetyl
FT transferase WbbJ"
FT /id="PRO_0000068738"
FT CONFLICT 168..176
FT /note="SIPENTVIA -> LFRKYCHC (in Ref. 1; AAC31635)"
FT /evidence="ECO:0000305"
FT CONFLICT 187..189
FT /note="NHE -> IMR (in Ref. 1; AAC31635)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 196 AA; 21675 MW; D1C2FA7D3B29A1B1 CRC64;
MILKLAKRYG LCGFIRLVRD VLLTRVFYRN CRIIRFPCYI RNDGSINFGE NFTSGVGLRL
DAFGRGVIFF SDNVQVNDYV HIASIESVTI GRDTLIASKV FITDHNHGSF KHSDPMSSPN
IPPDMRTLES SAVVIGQRVW LGENVTVLPG TIIGNGVVVG ANSVVRGSIP ENTVIAGVPA
KIIKKYNHET KLWEKA
