WBBK_ECOLI
ID WBBK_ECOLI Reviewed; 372 AA.
AC P37751;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Putative glycosyltransferase WbbK;
GN Name=wbbK; Synonyms=yefI; OrderedLocusNames=b2032, JW2017;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=7517390; DOI=10.1128/jb.176.13.4133-4143.1994;
RA Yao Z., Valvano M.A.;
RT "Genetic analysis of the O-specific lipopolysaccharide biosynthesis region
RT (rfb) of Escherichia coli K-12 W3110: identification of genes that confer
RT group 6 specificity to Shigella flexneri serotypes Y and 4a.";
RL J. Bacteriol. 176:4133-4143(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA Horiuchi T.;
RT "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 40.1-50.0 min region on the linkage map.";
RL DNA Res. 3:379-392(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-319.
RC STRAIN=K12 / WG1;
RX PubMed=7517391; DOI=10.1128/jb.176.13.4144-4156.1994;
RA Stevenson G., Neal B., Liu D., Hobbs M., Packer N.H., Batley M.,
RA Redmond J.W., Lindquist L., Reeves P.R.;
RT "Structure of the O antigen of Escherichia coli K-12 and the sequence of
RT its rfb gene cluster.";
RL J. Bacteriol. 176:4144-4156(1994).
RN [6]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 149-372.
RC STRAIN=K12 / WG1;
RX PubMed=7512872; DOI=10.1099/13500872-140-1-49;
RA Liu D., Reeves P.R.;
RT "Escherichia coli K12 regains its O antigen.";
RL Microbiology 140:49-57(1994).
CC -!- FUNCTION: May be a glycosyltransferase involved in the transfer of UDP-
CC GalF and UDP-glucose.
CC -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC biosynthesis.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Peripheral
CC membrane protein {ECO:0000305}.
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DR EMBL; U03041; AAC31636.1; -; Genomic_DNA.
DR EMBL; U00096; AAC75093.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15874.1; -; Genomic_DNA.
DR EMBL; U09876; AAB88407.1; -; Genomic_DNA.
DR EMBL; L19537; AAB49381.1; -; Genomic_DNA.
DR PIR; I69647; I69647.
DR RefSeq; NP_416536.1; NC_000913.3.
DR RefSeq; WP_000520320.1; NZ_LN832404.1.
DR AlphaFoldDB; P37751; -.
DR SMR; P37751; -.
DR BioGRID; 4261357; 336.
DR BioGRID; 850902; 1.
DR DIP; DIP-11874N; -.
DR IntAct; P37751; 23.
DR STRING; 511145.b2032; -.
DR CAZy; GT4; Glycosyltransferase Family 4.
DR jPOST; P37751; -.
DR PaxDb; P37751; -.
DR PRIDE; P37751; -.
DR EnsemblBacteria; AAC75093; AAC75093; b2032.
DR EnsemblBacteria; BAA15874; BAA15874; BAA15874.
DR GeneID; 946555; -.
DR KEGG; ecj:JW2017; -.
DR KEGG; eco:b2032; -.
DR PATRIC; fig|1411691.4.peg.219; -.
DR EchoBASE; EB1928; -.
DR eggNOG; COG0438; Bacteria.
DR HOGENOM; CLU_066447_0_0_6; -.
DR InParanoid; P37751; -.
DR OMA; VFPSYIE; -.
DR PhylomeDB; P37751; -.
DR BioCyc; EcoCyc:EG11985-MON; -.
DR UniPathway; UPA00030; -.
DR PRO; PR:P37751; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IBA:GO_Central.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IBA:GO_Central.
DR InterPro; IPR001296; Glyco_trans_1.
DR Pfam; PF00534; Glycos_transf_1; 1.
PE 4: Predicted;
KW Cell inner membrane; Cell membrane; Lipopolysaccharide biosynthesis;
KW Membrane; Reference proteome; Transferase.
FT CHAIN 1..372
FT /note="Putative glycosyltransferase WbbK"
FT /id="PRO_0000169121"
SQ SEQUENCE 372 AA; 43188 MW; F92A0D4E71EBAF31 CRC64;
MGKSIVVVSA VNFTTGGPFT ILKKFLAATN NKENVSFIAL VHSAKELKES YPWVKFIEFP
EVKGSWLKRL HFEYVVCKKL SKELNATHWI CLHDITANVV TKKRYVYCHN PAPFYKGILF
REILMEPSFF LFKMLYGLIY KINIKKNTAV FVQQFWMKEK FIKKYSINNI IVSRPEIKLS
DKSQLTDDDS QFKNNPSELT IFYPAVPRVF KNYELIISAA RKLKEQSNIK FLLTISGTEN
AYAKYIISLA EGLDNVHFLG YLDKEKIDHC YNISDIVCFP SRLETWGLPL SEAKERGKWV
LASDFPFTRE TLGSYEKKAF FDSNNDDMLV KLIIDFKKGN LKKDISDANF IYRNENVLVG
FDELVNFITE EH
