WBJE_PSEAI
ID WBJE_PSEAI Reviewed; 400 AA.
AC Q8KIU8; Q9KIC8; Q9XC58;
DT 25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 25-JUL-2003, sequence version 2.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Probable glycosyltransferase WbjE;
DE EC=2.4.-.-;
GN Name=wbjE;
OS Pseudomonas aeruginosa.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 29260 / PA103;
RX PubMed=10400585; DOI=10.1128/jb.181.14.4275-4284.1999;
RA Dean C.R., Franklund C.V., Retief J.D., Coyne M.J. Jr., Hatano K.,
RA Evans D.J., Pier G.B., Goldberg J.B.;
RT "Characterization of the serogroup O11 O-antigen locus of Pseudomonas
RT aeruginosa PA103.";
RL J. Bacteriol. 181:4275-4284(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=PAO17;
RX PubMed=10828401; DOI=10.1111/j.1574-6968.2000.tb09137.x;
RA Dean C.R., Goldberg J.B.;
RT "The wbpM gene in Pseudomonas aeruginosa serogroup O17 resides on a cryptic
RT copy of the serogroup O11 O antigen gene locus.";
RL FEMS Microbiol. Lett. 187:59-63(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=PAO11, and PAO17;
RX PubMed=12057956; DOI=10.1128/jb.184.13.3614-3622.2002;
RA Raymond C.K., Sims E.H., Kas A., Spencer D.H., Kutyavin T.V., Ivey R.G.,
RA Zhou Y., Kaul R., Clendenning J.B., Olson M.V.;
RT "Genetic variation at the O-antigen biosynthetic locus in Pseudomonas
RT aeruginosa.";
RL J. Bacteriol. 184:3614-3622(2002).
CC -!- PATHWAY: Bacterial outer membrane biogenesis; LPS O-antigen
CC biosynthesis.
CC -!- MISCELLANEOUS: The O-antigen locus is highly variable and differs
CC considerably between different serogroups of Pseudomonas aeruginosa.
CC -!- SIMILARITY: Belongs to the glycosyltransferase group 1 family.
CC Glycosyltransferase 4 subfamily. {ECO:0000305}.
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DR EMBL; AF147795; AAD45268.1; -; Genomic_DNA.
DR EMBL; AF236052; AAF72957.1; -; Genomic_DNA.
DR EMBL; AF498402; AAM27578.1; -; Genomic_DNA.
DR EMBL; AF498409; AAM27680.1; -; Genomic_DNA.
DR RefSeq; WP_023100915.1; NZ_VOKZ01000053.1.
DR RefSeq; WP_071535098.1; NZ_LODH01000001.1.
DR AlphaFoldDB; Q8KIU8; -.
DR SMR; Q8KIU8; -.
DR CAZy; GT4; Glycosyltransferase Family 4.
DR UniPathway; UPA00281; -.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009243; P:O antigen biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR028098; Glyco_trans_4-like_N.
DR Pfam; PF13579; Glyco_trans_4_4; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase; Lipopolysaccharide biosynthesis; Transferase.
FT CHAIN 1..400
FT /note="Probable glycosyltransferase WbjE"
FT /id="PRO_0000080313"
FT VARIANT 56
FT /note="D -> E (in strain: PA011 and PA103)"
FT VARIANT 342
FT /note="N -> S (in strain: PA011)"
SQ SEQUENCE 400 AA; 44558 MW; 8B7FCD511F0E1E16 CRC64;
MARIFVVSEY VGANQNSTGY YWEKIIGKMQ REFGGLTVIF PLTAGETPPV VSPSVDQECF
KFPRSNKNRL LSRGLAQIFQ AFLFSVKLTS RARRGDVVLS GTNPALLLMT FPLLRYALGF
KWVLLVHDVF PENLVPAGVL KKDSIAYRLL RRLFSFIYSS ADRLVVIGRD MEALMKEKVN
DPRSLVFISN WACEKEVFPV PREDAPFINI PEWKGKRVFQ FFGNVGRLQG IENILSAIQL
VKNEKAAFAF IGDGALVDSV KKHALEDQCA RLRYFGRLPL AEKNFGLAAC DVALVTLEEG
MFGLGVPSKA YFSMAADKPI LAVMEKGAEI SRIIDETGIG WNCPPNDPVA LARLIDEICE
LDLSSLGGVP RSVLQQNYSE YISLEKFAAC VRPLLSESKI