ID   WBP2L_MACFA             Reviewed;         255 AA.
AC   Q4R3M1;
DT   29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Postacrosomal sheath WW domain-binding protein;
DE   AltName: Full=WW domain-binding protein 2-like;
GN   Name=WBP2NL; Synonyms=PAWP; ORFNames=QtsA-15969;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in meiotic resumption and pronuclear
CC       formation, mediated by a WW domain-signaling pathway during
CC       fertilization. {ECO:0000250}.
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DR   EMBL; AB179245; BAE02296.1; -; mRNA.
DR   AlphaFoldDB; Q4R3M1; -.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0033011; C:perinuclear theca; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; IEA:InterPro.
DR   GO; GO:0050699; F:WW domain binding; IEA:InterPro.
DR   GO; GO:0007343; P:egg activation; IEA:InterPro.
DR   GO; GO:0035038; P:female pronucleus assembly; IEA:InterPro.
DR   GO; GO:0035039; P:male pronucleus assembly; IEA:InterPro.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR004182; GRAM.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR044852; WBP2-like.
DR   InterPro; IPR033597; WBP2NL.
DR   PANTHER; PTHR31606; PTHR31606; 2.
DR   PANTHER; PTHR31606:SF2; PTHR31606:SF2; 2.
DR   Pfam; PF02893; GRAM; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat.
FT   CHAIN           1..255
FT                   /note="Postacrosomal sheath WW domain-binding protein"
FT                   /id="PRO_0000289129"
FT   DOMAIN          15..87
FT                   /note="GRAM"
FT   REPEAT          139..145
FT                   /note="1"
FT   REPEAT          146..152
FT                   /note="2"
FT   REPEAT          153..159
FT                   /note="3"
FT   REPEAT          160..166
FT                   /note="3"
FT   REPEAT          167..173
FT                   /note="4"
FT   REPEAT          174..180
FT                   /note="5"
FT   REPEAT          202..208
FT                   /note="6"
FT   REGION          139..208
FT                   /note="6 X 7 AA tandem repeat of Y-G-X-P-P-X-G"
FT   REGION          180..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          204..255
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           171..174
FT                   /note="PPxY motif"
SQ   SEQUENCE   255 AA;  25938 MW;  8FC5D16F22284DA7 CRC64;
     MAVNQSHTEN RRGVLIPNGE SLLKQSLNVE LSFPRQSEGS NVFNGTKTGT LFLTSYRVIF
     ITSHSINGPM LSFMMPFDLI TNLTVEQPVF AANFIKGTIQ AAPYGGWEGQ ATFKLVFRNG
     GAIEFAQLMV KAASSVIAYG APPAGYGAPP AGYGAPPPGY GAPPAGYGAP PPGYGAPPAG
     YGAQPAGNEG PPVGYRASPA GYGAPPLGYE APPAGNEGLP AGYRASPAGS GARPHESAAA
     QAPENEASLP SASSS