ID   WCAB_ECO57              Reviewed;         162 AA.
AC   P0ACD0; P77558;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Putative colanic acid biosynthesis acetyltransferase WcaB;
DE            EC=2.3.1.-;
GN   Name=wcaB; OrderedLocusNames=Z3222, ECs2863;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- PATHWAY: Slime biogenesis; slime polysaccharide biosynthesis.
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC       {ECO:0000305}.
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DR   EMBL; AE005174; AAG57118.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB36286.1; -; Genomic_DNA.
DR   PIR; B85832; B85832.
DR   PIR; G90986; G90986.
DR   RefSeq; NP_310890.1; NC_002695.1.
DR   RefSeq; WP_000888740.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0ACD0; -.
DR   SMR; P0ACD0; -.
DR   STRING; 155864.EDL933_3131; -.
DR   EnsemblBacteria; AAG57118; AAG57118; Z3222.
DR   EnsemblBacteria; BAB36286; BAB36286; ECs_2863.
DR   GeneID; 66674044; -.
DR   GeneID; 912644; -.
DR   KEGG; ece:Z3222; -.
DR   KEGG; ecs:ECs_2863; -.
DR   PATRIC; fig|386585.9.peg.2996; -.
DR   eggNOG; COG1045; Bacteria.
DR   HOGENOM; CLU_051638_10_2_6; -.
DR   OMA; FGRWRYT; -.
DR   UniPathway; UPA00936; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0009001; F:serine O-acetyltransferase activity; IEA:InterPro.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0045228; P:slime layer polysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd03354; LbH_SAT; 1.
DR   InterPro; IPR024027; Colanic_acid_synth_WcaB.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR018357; Hexapep_transf_CS.
DR   InterPro; IPR045304; LbH_SAT.
DR   InterPro; IPR005881; Ser_O-AcTrfase.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   Pfam; PF00132; Hexapep; 1.
DR   PIRSF; PIRSF000441; CysE; 1.
DR   SUPFAM; SSF51161; SSF51161; 1.
DR   TIGRFAMs; TIGR04016; WcaB; 1.
DR   PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Lipopolysaccharide biosynthesis; Reference proteome;
KW   Repeat; Transferase.
FT   CHAIN           1..162
FT                   /note="Putative colanic acid biosynthesis acetyltransferase
FT                   WcaB"
FT                   /id="PRO_0000068734"
SQ   SEQUENCE   162 AA;  17616 MW;  F2462F836F3FB3AD CRC64;
     MLEDLRANSW SLRPCCMVLA YRVAHFCSVW RKKNVLNNLW AAPLLVLYRI ITECFFGYEI
     QAAATIGRRF TIHHGYAVVI NKNVVAGDDF TIRHGVTIGN RGADNMACPH IGNGVELGAN
     VIILGDITLG NNVTVGAGSV VLDSVPDNAL VVGEKARVKV IK