ID   WCAB_ECOLI              Reviewed;         162 AA.
AC   P0ACC9; P77558;
DT   08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Putative colanic acid biosynthesis acetyltransferase WcaB;
DE            EC=2.3.1.-;
GN   Name=wcaB; OrderedLocusNames=b2058, JW2043;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=8759852; DOI=10.1128/jb.178.16.4885-4893.1996;
RA   Stevenson G., Andrianopoulos K., Hobbs M., Reeves P.R.;
RT   "Organization of the Escherichia coli K-12 gene cluster responsible for
RT   production of the extracellular polysaccharide colanic acid.";
RL   J. Bacteriol. 178:4885-4893(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097040; DOI=10.1093/dnares/3.6.379;
RA   Itoh T., Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K.,
RA   Kasai H., Kimura S., Kitakawa M., Kitagawa M., Makino K., Miki T.,
RA   Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S., Nakamura Y.,
RA   Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G., Seki Y.,
RA   Sivasundaram S., Tagami H., Takeda J., Takemoto K., Wada C., Yamamoto Y.,
RA   Horiuchi T.;
RT   "A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 40.1-50.0 min region on the linkage map.";
RL   DNA Res. 3:379-392(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- PATHWAY: Slime biogenesis; slime polysaccharide biosynthesis.
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC       {ECO:0000305}.
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DR   EMBL; U38473; AAC77837.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC75119.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA15911.1; -; Genomic_DNA.
DR   PIR; A64972; A64972.
DR   RefSeq; NP_416562.1; NC_000913.3.
DR   RefSeq; WP_000888740.1; NZ_SSUV01000030.1.
DR   AlphaFoldDB; P0ACC9; -.
DR   SMR; P0ACC9; -.
DR   BioGRID; 4260674; 269.
DR   DIP; DIP-48109N; -.
DR   IntAct; P0ACC9; 1.
DR   STRING; 511145.b2058; -.
DR   PaxDb; P0ACC9; -.
DR   PRIDE; P0ACC9; -.
DR   EnsemblBacteria; AAC75119; AAC75119; b2058.
DR   EnsemblBacteria; BAA15911; BAA15911; BAA15911.
DR   GeneID; 66674044; -.
DR   GeneID; 946573; -.
DR   KEGG; ecj:JW2043; -.
DR   KEGG; eco:b2058; -.
DR   PATRIC; fig|1411691.4.peg.193; -.
DR   EchoBASE; EB3340; -.
DR   eggNOG; COG1045; Bacteria.
DR   HOGENOM; CLU_051638_10_2_6; -.
DR   InParanoid; P0ACC9; -.
DR   OMA; FGRWRYT; -.
DR   PhylomeDB; P0ACC9; -.
DR   BioCyc; EcoCyc:G7103-MON; -.
DR   BioCyc; MetaCyc:G7103-MON; -.
DR   UniPathway; UPA00936; -.
DR   PRO; PR:P0ACC9; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0016407; F:acetyltransferase activity; ISS:EcoliWiki.
DR   GO; GO:0016413; F:O-acetyltransferase activity; IDA:EcoCyc.
DR   GO; GO:0009001; F:serine O-acetyltransferase activity; IBA:GO_Central.
DR   GO; GO:0009242; P:colanic acid biosynthetic process; IGC:EcoCyc.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0045228; P:slime layer polysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd03354; LbH_SAT; 1.
DR   InterPro; IPR024027; Colanic_acid_synth_WcaB.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR018357; Hexapep_transf_CS.
DR   InterPro; IPR045304; LbH_SAT.
DR   InterPro; IPR005881; Ser_O-AcTrfase.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   Pfam; PF00132; Hexapep; 1.
DR   PIRSF; PIRSF000441; CysE; 1.
DR   SUPFAM; SSF51161; SSF51161; 1.
DR   TIGRFAMs; TIGR04016; WcaB; 1.
DR   PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Lipopolysaccharide biosynthesis; Reference proteome;
KW   Repeat; Transferase.
FT   CHAIN           1..162
FT                   /note="Putative colanic acid biosynthesis acetyltransferase
FT                   WcaB"
FT                   /id="PRO_0000068733"
SQ   SEQUENCE   162 AA;  17616 MW;  F2462F836F3FB3AD CRC64;
     MLEDLRANSW SLRPCCMVLA YRVAHFCSVW RKKNVLNNLW AAPLLVLYRI ITECFFGYEI
     QAAATIGRRF TIHHGYAVVI NKNVVAGDDF TIRHGVTIGN RGADNMACPH IGNGVELGAN
     VIILGDITLG NNVTVGAGSV VLDSVPDNAL VVGEKARVKV IK