WCAF_SHIFL
ID WCAF_SHIFL Reviewed; 182 AA.
AC P0ACD3; P71240; P76383;
DT 08-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Putative colanic acid biosynthesis acetyltransferase WcaF;
DE EC=2.3.1.-;
GN Name=wcaF; OrderedLocusNames=SF2117, S2240;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- PATHWAY: Slime biogenesis; slime polysaccharide biosynthesis.
CC -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC {ECO:0000305}.
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DR EMBL; AE005674; AAN43656.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP17485.1; -; Genomic_DNA.
DR RefSeq; NP_707949.1; NC_004337.2.
DR RefSeq; WP_001153547.1; NZ_WPGW01000076.1.
DR AlphaFoldDB; P0ACD3; -.
DR SMR; P0ACD3; -.
DR STRING; 198214.SF2117; -.
DR EnsemblBacteria; AAN43656; AAN43656; SF2117.
DR EnsemblBacteria; AAP17485; AAP17485; S2240.
DR GeneID; 1026791; -.
DR GeneID; 58459758; -.
DR KEGG; sfl:SF2117; -.
DR KEGG; sfx:S2240; -.
DR PATRIC; fig|198214.7.peg.2525; -.
DR HOGENOM; CLU_051638_7_2_6; -.
DR OMA; IWAPWNL; -.
DR OrthoDB; 1878940at2; -.
DR UniPathway; UPA00936; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:UniProt.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0045228; P:slime layer polysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR024005; Colanic_acid_synth_WcaF.
DR InterPro; IPR001451; Hexapep.
DR InterPro; IPR018357; Hexapep_transf_CS.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR Pfam; PF00132; Hexapep; 1.
DR SUPFAM; SSF51161; SSF51161; 1.
DR TIGRFAMs; TIGR04008; WcaF; 1.
DR PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE 3: Inferred from homology;
KW Acyltransferase; Lipopolysaccharide biosynthesis; Reference proteome;
KW Repeat; Transferase.
FT CHAIN 1..182
FT /note="Putative colanic acid biosynthesis acetyltransferase
FT WcaF"
FT /id="PRO_0000068737"
SQ SEQUENCE 182 AA; 19962 MW; 8AA5E672CA802442 CRC64;
MQDLSGFSVP KGFRGGNAIK VQLWWAVQAT IFAWSPQVLY RWRAFLLRLF GAKIGKNVVI
RPSVKITYPW KLTLGDYAWV GDDVNLYTLG EITIGAHSVI SQKSYLCTGS HDHASQHFTI
NATPIVIGEK CWLATDVFVA PGVTIGDGTV VGARSSVFKS LPANVVCRGN PAVVIRERVE
TE
